# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1064501 | B | Inhibition of human P2Y12 receptor expressed in CHO cells | Homo sapiens | 84 | cell-based format | Scientific Literature | ||
2. | ALA1064502 | F | Antiplatelet activity in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation | Homo sapiens | 84 | cell-free format | Scientific Literature | ||
3. | ALA1070705 | F | Antiplatelet activity in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation relative to AZD-6140 | Homo sapiens | 78 | cell-free format | Scientific Literature | ||
4. | ALA1070706 | A | Metabolic stability in rat microsomes | Rattus norvegicus | 84 | microsome format | Scientific Literature | ||
5. | ALA1070707 | A | Metabolic stability in human microsomes | Homo sapiens | 84 | microsome format | Scientific Literature | ||
6. | ALA1070708 | A | Clearance in Sprague-Dawley rat at 2 mg/kg, iv and 5 mg/kg, po | Rattus norvegicus | 15 | organism-based format | Scientific Literature | ||
7. | ALA1070709 | A | Volume of distribution at steady state in Sprague-Dawley rat at 2 mg/kg, iv and 5 mg/kg, po | Rattus norvegicus | 15 | organism-based format | Scientific Literature | ||
8. | ALA1070710 | A | Effective half life in Sprague-Dawley rat at 2 mg/kg, iv and 5 mg/kg, po | Rattus norvegicus | 15 | organism-based format | Scientific Literature | ||
9. | ALA1070711 | A | Oral bioavailability in Sprague-Dawley rat at 5 mg/kg, po | Rattus norvegicus | 9 | organism-based format | Scientific Literature | ||
10. | ALA1070712 | B | Inhibition of human ERG | Homo sapiens | 2 | single protein format | Scientific Literature | ||
11. | ALA1070713 | T | Toxicity in rat administered as single dose | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
12. | ALA1070715 | P | Solubility at pH 2.0 | 2 | small-molecule physicochemical format | Scientific Literature | |||
13. | ALA1070716 | P | Solubility at pH 6.5 | 2 | small-molecule physicochemical format | Scientific Literature | |||
14. | ALA1070717 | P | Solubility at pH 9.0 | 2 | small-molecule physicochemical format | Scientific Literature | |||
15. | ALA1070718 | A | Protein binding in human plasma assessed as fraction unbound at 0.2 uM | Homo sapiens | 2 | cell-free format | Scientific Literature | ||
16. | ALA1070719 | A | Protein binding in human plasma assessed as fraction unbound at 2 uM | Homo sapiens | 2 | cell-free format | Scientific Literature | ||
17. | ALA1070720 | A | Protein binding in human plasma assessed as fraction unbound at 10 uM | Homo sapiens | 2 | cell-free format | Scientific Literature | ||
18. | ALA1070721 | B | Inhibition of P2Y13 at 10 uM | 1 | single protein format | Scientific Literature | |||
19. | ALA1070723 | F | Antiplatelet activity in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation by chronolog PRP aggregometry assay | Homo sapiens | 2 | cell-free format | Scientific Literature | ||
20. | ALA1070724 | B | Inhibition of human P2Y12 receptor expressed in CHO cells in presence of 0.4% human serum albumin | Homo sapiens | 2 | cell-based format | Scientific Literature |