# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1838946 | F | Antiproliferative activity against chinese hamster PC43-10 expressing human RFC assessed as reduction of viable cells after 96 hrs | Cricetulus griseus | 9 | assay format | Scientific Literature | ||
2. | ALA1838947 | A | Antiproliferative activity against chinese hamster R2 cells assessed as reduction of viable cells after 96 hrs | Cricetulus griseus | 9 | cell-based format | Scientific Literature | ||
3. | ALA1838948 | F | Antiproliferative activity against chinese hamster RT16 cells expressing human FRalpha assessed as reduction of viable cells after 96 hrs | Cricetulus griseus | 9 | cell-based format | Scientific Literature | ||
4. | ALA1838949 | F | Antiproliferative activity against chinese hamster RT16 cells expressing human FRalpha assessed as reduction of viable cells after 96 hrs in the presence of 200 nM folic acid | Cricetulus griseus | 9 | cell-based format | Scientific Literature | ||
5. | ALA1838950 | F | Antiproliferative activity against chinese hamster D4 cells expressing human FRbeta assessed as reduction of viable cells after 96 hrs | Cricetulus griseus | 9 | cell-based format | Scientific Literature | ||
6. | ALA1838951 | F | Antiproliferative activity against chinese hamster D4 cells expressing human FRbeta assessed as reduction of viable cells after 96 hrs in the presence of 200 nM folic acid | Cricetulus griseus | 9 | cell-based format | Scientific Literature | ||
7. | ALA1838952 | F | Antiproliferative activity against chinese hamster R2 cells expressing human PCFT assessed as reduction of viable cells after 96 hrs | Cricetulus griseus | 9 | cell-based format | Scientific Literature | ||
8. | ALA1838953 | A | Antiproliferative activity against chinese hamster R2(VC) cells expressing human PCFT assessed as reduction of viable cells after 96 hrs | Cricetulus griseus | 9 | assay format | Scientific Literature | ||
9. | ALA1838954 | F | Antiproliferative activity against human KB cells expressing human RFC, FRalpha and PCFT assessed as reduction of viable cells after 96 hrs | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
10. | ALA1838955 | F | Antiproliferative activity against human KB cells expressing human RFC, FRalpha and PCFT assessed as reduction of viable cells after 96 hrs in the presence of 200 nM folic acid | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
11. | ALA1838956 | F | Antiproliferative activity against human IGROV1 cells expressing human RFC, FRalpha and PCFT assessed as reduction of viable cells after 96 hrs | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
12. | ALA1838957 | F | Antiproliferative activity against human IGROV1 cells expressing human RFC, FRalpha and PCFT assessed as reduction of viable cells after 96 hrs in the presence of 200 nM folic acid | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
13. | ALA1838958 | F | Ratio of IC50 for chinese hamster RT16 cells expressing FRalpha cells to IC50 for chinese hamster D4 cells expressing human FRbeta | Cricetulus griseus | 2 | cell-based format | Scientific Literature | ||
14. | ALA1838959 | F | Antiproliferative activity against chinese hamster R2 cells expressing human PCFT assessed as inhibition of colony formation after 10 to 14 days | Cricetulus griseus | 4 | cell-based format | Scientific Literature | ||
15. | ALA1839674 | B | Inhibition of human RFC-mediated [3H]MTX uptake in chinese hamster PC43-10 cells at 10 uM after 2 mins relative to control | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
16. | ALA1837097 | B | Induction of current in human PCFT expressed in xenopus oocyte at 5 uM at holding potential -90 mV by voltage clamp assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
17. | ALA1837098 | B | Inhibition of human PCFT-mediated [3H]MTX uptake ectopically expressed in chinese hamster R2 cells at 10 uM at pH 5.5 to 7.2 | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
18. | ALA1837101 | B | Inhibition of human PCFT-mediated [3H]MTX uptake expressed in chinese hamster R2 cells at pH 5.5 by dixon plot analysis relative to PMX | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
19. | ALA1837102 | B | Inhibition of human PCFT-mediated [3H]MTX uptake expressed in chinese hamster R2 cells at pH 6.8 by dixon plot analysis relative to PMX | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
20. | ALA1837108 | F | Decrease in intracellular ATP concentration in chinese hamster R2 cells expressing human PCFT at 1 uM after 24 hrs by HPLC relative to control at pH 6.8 | Cricetulus griseus | 4 | cell-based format | Scientific Literature |