| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1068015 | B | Inhibition of N type calcium channel alpha-1b/alpha-2-delta-1/beta-1b expressed in HEK293 cells at holding potential of -100 mV by whole-cell patch clamp method | 50 | cell-based format | Scientific Literature | |||
| 2. | ALA1068016 | B | Inhibition of L type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells in presence of -100 mV holding potential by whole-cell patch clamp method | 13 | cell-based format | Scientific Literature | |||
| 3. | ALA1068017 | B | Inhibition of L-type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells by FLIPR method | 23 | cell-based format | Scientific Literature | |||
| 4. | ALA1068018 | P | Aqueous solubility at pH 7.4 | 12 | small-molecule physicochemical format | Scientific Literature | |||
| 5. | ALA1071406 | F | Analgesic activity in Sprague-Dawley rat assessed as inhibition of spinal nerve injury-induced mechanical allodynia at 30 mg/kg, po after 60-90 mins | Rattus norvegicus | 9 | organism-based format | Scientific Literature | ||
| 6. | ALA1071407 | F | Analgesic activity in Sprague-Dawley rat assessed as inhibition of spinal nerve injury-induced thermal hyperalgesia at 30 mg/kg, po after 60-90 mins | Rattus norvegicus | 9 | organism-based format | Scientific Literature | ||
| 7. | ALA1071408 | A | Cmax at Sprague-Dawley rat at 2 mg/kg, iv | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 8. | ALA1071409 | A | AUC (0 to 24 hrs) at Sprague-Dawley rat at 2 mg/kg, iv | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 9. | ALA1071410 | A | Half life at Sprague-Dawley rat at 2 mg/kg, iv | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 10. | ALA1071411 | A | Cmax at Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 11. | ALA1071412 | A | Tmax at Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 12. | ALA1071413 | A | AUC (0 to 24 hrs) at Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 13. | ALA1071414 | A | Half life at Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 14. | ALA1071415 | A | Oral bioavailability at Sprague-Dawley rat at 10 mg/kg | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 15. | ALA1104120 | B | Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole cell patch clamp assay | Rattus norvegicus | 25 | cell-based format | Scientific Literature | ||
| 16. | ALA1116628 | B | Blocking of rat Voltage-dependent L-type calcium channel alpha1c/alpha2delta-1/beta1b activity expressed in HEK293 cells assessed as whole cell current by whole cell patch clamp assay | Rattus norvegicus | 10 | cell-based format | Scientific Literature | ||
| 17. | ALA1116629 | B | Selectivity ratio of IC50 for rat Voltage-dependent L-type calcium channel to IC50 for rat N-type calcium channel | Rattus norvegicus | 10 | assay format | Scientific Literature |
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