| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA636394 | A | Delta logD (logD6.5 - logD7.4) | 152 | assay format | Scientific Literature | |||
| 2. | ALA646647 | P | Partition coefficient (logD6.5) | 153 | small-molecule physicochemical format | Scientific Literature | |||
| 3. | ALA645153 | P | Ionization constant (pKa) | 204 | small-molecule physicochemical format | Scientific Literature | |||
| 4. | ALA633098 | A | Oral bioavailability in human | Homo sapiens | 184 | organism-based format | Scientific Literature | ||
| 5. | ALA646167 | B | Binding affinity towards human Alpha-1C adrenergic receptor by the displacement of [3H]prazosin | 7 | single protein format | Scientific Literature | |||
| 6. | ALA645760 | F | Compound was evaluated for hypotensive activity mediated by Alpha-2 adrenergic receptor; no data | 3 | assay format | Scientific Literature | |||
| 7. | ALA648058 | B | Displacement of [3H]RX-821002 from alpha-2 adrenergic receptor of calf frontal cortex membranes | Bos taurus | 8 | tissue-based format | Scientific Literature | ||
| 8. | ALA643580 | F | Agonistic activity towards human Alpha-2A adrenergic receptor was measured as ability to inhibit forskolin-stimulated synthesis of cyclic adenosine monophosphate | 6 | assay format | Scientific Literature | |||
| 9. | ALA643229 | B | Binding affinity towards human Alpha-2A adrenergic receptor by the displacement of [3H]rauwolscine | 7 | single protein format | Scientific Literature | |||
| 10. | ALA644765 | F | Agonistic activity towards human Alpha-2B adrenergic receptor was measured as ability to inhibit forskolin-stimulated synthesis of cyclic adenosine monophosphate | 6 | assay format | Scientific Literature | |||
| 11. | ALA645108 | B | Binding affinity towards human Alpha-2B adrenergic receptor by the displacement of [3H]rauwolscine | 7 | single protein format | Scientific Literature | |||
| 12. | ALA649236 | F | Agonistic activity towards human Alpha-2C adrenergic receptor was measured as ability to inhibit forskolin-stimulated synthesis of cyclic adenosine monophosphate | 6 | assay format | Scientific Literature | |||
| 13. | ALA649246 | B | Binding affinity towards human Alpha-2C adrenergic receptor by the displacement of [3H]rauwolscine | 7 | single protein format | Scientific Literature | |||
| 14. | ALA643753 | B | Binding affinity towards human Alpha-1A adrenergic receptor by the displacement of [3H]prazosin | 7 | single protein format | Scientific Literature | |||
| 15. | ALA645566 | B | Binding affinity towards human Alpha-1B adrenergic receptor by the displacement of [3H]prazosin | 7 | single protein format | Scientific Literature | |||
| 16. | ALA858411 | B | Displacement of [3H]idazoxan from I2 imidazoline binding sites (I2Bs) of rabbit renal cortex membranes | Oryctolagus cuniculus | 8 | assay format | Scientific Literature | ||
| 17. | ALA698299 | B | Displacement of [3H]clonidine from imidazoline receptor I-1 of bovine chromaffin cell membranes | Bos taurus | 8 | assay format | Scientific Literature | ||
| 18. | ALA989165 | B | Displacement of [125I]PIC from human alpha2 adrenoceptors expressed in CHO cells | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 19. | ALA989166 | B | Displacement of [125I]PIC from human imidazoline receptor 1 in human platelets analyzed under norepinephrine mask of alpha 2AR | Homo sapiens | 14 | assay format | Scientific Literature | ||
| 20. | ALA989168 | B | Selectivity ratio of pKi for human imidazoline receptor 1 to pKi for human alpha2 adrenoceptors | Homo sapiens | 12 | assay format | Scientific Literature |
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