# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA684849 | Functional | Ke value for naloxone versus compound in the guinea pig ileum (GPI) in order to distinguish between mu- and delta-mediated effects | Cavia porcellus | 7 | ALA1123636 | organism-based format | Scientific Literature | |
2. | ALA687944 | Functional | Opioid agonist potencies was determined by electrically stimulated guinea pig ileum (GPI) | Cavia porcellus | 2 | ALA1123636 | organism-based format | Scientific Literature | |
3. | ALA846229 | Binding | Potency ratio is the ratio of morphine IC50 to that of compound on same tissue | 10 | ALA1123225 | assay format | Scientific Literature | ||
4. | ALA881845 | Binding | Relative potency is the bivalent potency ratio divided by monovalent potency ratio | 10 | ALA1123225 | assay format | Scientific Literature | ||
5. | ALA852903 | Binding | Selectivity ratio is expressed as ratios of Ki values between mu, kappa, delta opioid receptors respectively; 1:0.03:0.38 | 1 | ALA1123225 | protein format | Scientific Literature | ||
6. | ALA755961 | Binding | Binding affinity of Opioid receptor mu 1 by the displacement of mu-selective [3H]DAGO from brain membrane preparations. | Cavia porcellus | 5 | ALA1123636 | assay format | Scientific Literature | |
7. | ALA752187 | Binding | Displacement of [3H]naloxone from Opioid receptor mu 1 in guinea pig brain membrane | Cavia porcellus | 15 | ALA1123225 | cell membrane format | Scientific Literature | |
8. | ALA751876 | Binding | Affinity comparison to [3H]naloxone for Opioid receptor mu 1 in guinea pig brain membrane | Cavia porcellus | 15 | ALA1123225 | cell membrane format | Scientific Literature | |
9. | ALA755012 | Functional | Activity against opioid receptor in guinea pig ileum longitudinal muscle | Cavia porcellus | 10 | ALA1123225 | tissue-based format | Scientific Literature | |
10. | ALA873912 | Binding | Displacement of [3H]DADLE from Opioid receptor kappa 1 in guinea pig brain membrane | Cavia porcellus | 15 | ALA1123225 | cell membrane format | Scientific Literature | |
11. | ALA753669 | Binding | Binding affinity of Opioid receptor delta 1 by the displacement of delta-selective [3H]DSLET from brain membrane preparations. | Cavia porcellus | 7 | ALA1123636 | assay format | Scientific Literature | |
12. | ALA758249 | Binding | Affinity comparison to [3H]DADLE for Opioid receptor kappa 1 in guinea pig brain membrane | Cavia porcellus | 15 | ALA1123225 | cell membrane format | Scientific Literature | |
13. | ALA753852 | Binding | Displacement of [3H]EK from Opioid receptor delta 1 in guinea pig brain membrane | Cavia porcellus | 14 | ALA1123225 | cell membrane format | Scientific Literature | |
14. | ALA756036 | Binding | Affinity comparison to [3H]EK for Opioid receptor delta 1 in guinea pig brain membrane | Cavia porcellus | 15 | ALA1123225 | cell membrane format | Scientific Literature | |
15. | ALA734130 | Functional | Analgesic potency (antinociceptive activity) (administered icv) at peak time of 20 min in male Swiss-Webster mice | Mus musculus | 4 | ALA1123636 | organism-based format | Scientific Literature | |
16. | ALA735753 | Functional | Opioid agonist potencies was determined by mouse vas deferens (MVD) | Mus musculus | 7 | ALA1123636 | organism-based format | Scientific Literature |