# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1115707 | F | Antifibrotic activity in rat 1097 cells assessed as inhibition of TGF-beta-stimulated [3H]proline incorporation in to collagen at 100 uM | Rattus norvegicus | 21 | ALA1153705 | cell-based format | Scientific Literature | |
2. | ALA4822994 | B | Inhibition of N-terminal His-tagged human JMJD7 (1 to 316 residues) expressed in Escherichia coli BL21 (DE3) luciferase based succinate-gloTM JmjC demethylase/hydroxylase assay | Homo sapiens | 7 | ALA4819143 | assay format | Scientific Literature | |
3. | ALA4833456 | B | Inhibition of 8-anilinonaphthalene-l-sulfonic acid binding to TTR V3OM mutant (unknown origin) expressed in Escherichia coli assessed as ANS saturation ratio at 400 uM incubated for 1 hr in presence of 7.5 uM ANS by fluorescence method (Rvb = 56 +/- 2.3%) | Homo sapiens | 43 | ALA4831538 | assay format | Scientific Literature | |
4. | ALA4833457 | B | Inhibition of 8-anilinonaphthalene-l-sulfonic acid binding to TTR V3OM mutant (unknown origin) expressed in Escherichia coli at 400 uM incubated for 1 hr in presence of 75 uM ANS by fluorescence method (Rvb = 91 +/- 0.92%) | Homo sapiens | 43 | ALA4831538 | assay format | Scientific Literature | |
5. | ALA4833459 | B | Stabilization of TTR V3OM mutant (unknown origin) assessed as acid-mediated protein aggregation inhibition ratio at 4 uM incubated for 1 week by absorbance method | Homo sapiens | 43 | ALA4831538 | single protein format | Scientific Literature | |
6. | ALA4833460 | B | Stabilization of TTR V3OM mutant (unknown origin) assessed as acid-mediated protein aggregation inhibition ratio at 10 uM incubated for 1 week by absorbance method | Homo sapiens | 43 | ALA4831538 | single protein format | Scientific Literature |