# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA651539 | Functional | The ratio of survival time for treated divided by survival time of control x 100 at a dose of 12.5 mg/kg in B16 melanoma cells | Mus musculus | 1 | ALA1124841 | organism-based format | Scientific Literature | |
2. | ALA651540 | Functional | The ratio of survival time for treated divided by survival time of control x 100 at a dose of 25 mg/kg in B16 melanoma cells | Mus musculus | 2 | ALA1124841 | organism-based format | Scientific Literature | |
3. | ALA690212 | Functional | In vitro antimitotic activity against HeLa cells after 1 hr exposure to the compound | Homo sapiens | 8 | ALA1124841 | cell-based format | Scientific Literature | |
4. | ALA690213 | Functional | In vitro antimitotic activity against HeLa cells after 6 hours exposure | Homo sapiens | 75 | ALA1124841 | cell-based format | Scientific Literature | |
5. | ALA701563 | Functional | Compound was evaluated for cytotoxic activity against K562 human chronic myelogenous leukemia cell line using MTT assay | Homo sapiens | 9 | ALA1130804 | cell-based format | Scientific Literature | |
6. | ALA706400 | Functional | The ratio of survival time for treated divided by survival time of control x 100 at a dose of 12.5 mg/kg in L1210 leukemia cells | Mus musculus | 1 | ALA1124841 | organism-based format | Scientific Literature | |
7. | ALA706401 | Functional | The ratio of survival time for treated divided by survival time of control x 100 at a dose of 25 mg/kg in L1210 leukemia cells | Mus musculus | 3 | ALA1124841 | organism-based format | Scientific Literature | |
8. | ALA706402 | Functional | The ratio of survival time for treated divided by survival time of control x 100 at a dose of 50 mg/kg in L1210 leukemia cells | Mus musculus | 3 | ALA1124841 | organism-based format | Scientific Literature | |
9. | ALA706403 | Functional | The ratio of survival time for treated divided by survival time of control x 100 at a dose of 6.25 mg/kg in L1210 leukemia cells | Mus musculus | 1 | ALA1124841 | organism-based format | Scientific Literature | |
10. | ALA832453 | Binding | Concentration required for 50% inhibition of tubulin polymerization | 47 | ALA1141176 | single protein format | Scientific Literature | ||
11. | ALA1039834 | Functional | Antiproliferative activity against human K562 cells after 5 days by MTT assay | Homo sapiens | 95 | ALA1152676 | cell-based format | Scientific Literature | |
12. | ALA1046047 | Functional | Cell cycle arrest in human K562 cells assessed as accumulation at G0/G1 phase at 20 nM after 24 hrs by propidium iodide staining-based flow cytometry | Homo sapiens | 25 | ALA1152676 | cell-based format | Scientific Literature | |
13. | ALA1046048 | Functional | Cell cycle arrest in human K562 cells assessed as accumulation at S phase at 20 nM after 24 hrs by propidium iodide staining-based flow cytometry | Homo sapiens | 25 | ALA1152676 | cell-based format | Scientific Literature | |
14. | ALA1046049 | Functional | Cell cycle arrest in human K562 cells assessed as accumulation at G2/M phase at 20 nM after 24 hrs by propidium iodide staining-based flow cytometry | Homo sapiens | 25 | ALA1152676 | cell-based format | Scientific Literature | |
15. | ALA1046050 | Binding | Inhibition of tubulin assembly by Woods method | 25 | ALA1152676 | assay format | Scientific Literature | ||
16. | ALA1046051 | Binding | Displacement of [3H]colchicine from tubulin assessed as bound colchicine at 0.05 to 10 mM incubated in dark for 2 hrs by scintillation spectroscopy | 25 | ALA1152676 | assay format | Scientific Literature | ||
17. | ALA1046052 | Binding | Binding affinity to tubulin in african green monkey Vero cells assessed as aberration of microtubule arrangement at 10 uM after 40 mins by immunohistochemistry | Chlorocebus sabaeus | 7 | ALA1152676 | cell-based format | Scientific Literature | |
18. | ALA816888 | Binding | Tested for inhibition of polymerization of tubulin | 1 | ALA1130804 | single protein format | Scientific Literature | ||
19. | ALA4002303 | Binding | Inhibition of cytoplasmic microtubule network assembly in rat-kangaroo PtK2 cells assessed as microtubule reassembly time measured post compound washout | Potorous tridactylus | 1 | ALA4000249 | cell-based format | Scientific Literature | |
20. | ALA4002304 | Binding | Inhibition of cytoplasmic microtubule network assembly in rat-kangaroo PtK2 cells assessed as time required to reorganize cytoplasmic microtubule network measured post compound washout | Potorous tridactylus | 1 | ALA4000249 | cell-based format | Scientific Literature |