# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3738851 | Functional | Renoprotective activity in pig LLC-PK1 cells assessed as reduction in cisplatin-induced toxicity at 125 uM preincubated for 2 hrs followed by cisplatin challenge for 24 hrs by MTT assay | Sus scrofa | 4 | ALA3734678 | cell-based format | Scientific Literature | |
2. | ALA3738852 | Functional | Renoprotective activity in pig LLC-PK1 cells assessed as reduction in cisplatin-induced cell shrank at 125 uM preincubated for 2 hrs followed by cisplatin challenge for 24 hrs by phase-contrast microscopic analysis | Sus scrofa | 4 | ALA3734678 | cell-based format | Scientific Literature | |
3. | ALA3738853 | Functional | Renoprotective activity in pig LLC-PK1 cells assessed as reduction in cisplatin-induced progressive condensation at 125 uM preincubated for 2 hrs followed by cisplatin challenge for 24 hrs by phase-contrast microscopic analysis | Sus scrofa | 4 | ALA3734678 | cell-based format | Scientific Literature | |
4. | ALA3738854 | Functional | Renoprotective activity in pig LLC-PK1 cells assessed as reduction in cisplatin-induced nucleus break-up at 125 uM preincubated for 2 hrs followed by cisplatin challenge for 24 hrs by phase-contrast microscopic analysis | Sus scrofa | 4 | ALA3734678 | cell-based format | Scientific Literature | |
5. | ALA3738855 | Functional | Renoprotective activity against cisplatin induced toxicity in pig LLC-PK1 cells assessed as reduction in apoptotic cells at 125 uM preincubated for 2 hrs followed by cisplatin challenge for 24 hrs annexin-V-FITC and propidium iodide staining based flow cytometry | Sus scrofa | 4 | ALA3734678 | cell-based format | Scientific Literature | |
6. | ALA3738856 | Binding | Inhibition of cisplatin-induced JNK phosphorylation in pig LLC-PK1 cells at 125 uM preincubated for 2 hrs followed by cisplatin challenge for 24 hrs by western blot analysis | Sus scrofa | 4 | ALA3734678 | cell-based format | Scientific Literature | |
7. | ALA3738857 | Binding | Inhibition of cisplatin-induced ERK phosphorylation in pig LLC-PK1 cells at 125 uM preincubated for 2 hrs followed by cisplatin challenge for 24 hrs by western blot analysis | Sus scrofa | 4 | ALA3734678 | cell-based format | Scientific Literature | |
8. | ALA3738858 | Binding | Inhibition of cisplatin-induced p38 phosphorylation in pig LLC-PK1 cells at 125 uM preincubated for 2 hrs followed by cisplatin challenge for 24 hrs by western blot analysis | Sus scrofa | 4 | ALA3734678 | cell-based format | Scientific Literature | |
9. | ALA3738859 | Functional | Renoprotective activity in pig LLC-PK1 cells assessed as inhibition of cisplatin-induced cleaved caspase-3 expression at 125 uM preincubated for 2 hrs followed by cisplatin challenge for 24 hrs by western blot analysis | Sus scrofa | 4 | ALA3734678 | cell-based format | Scientific Literature | |
10. | ALA3738860 | Functional | Renoprotective activity in pig LLC-PK1 cells assessed as reduction in cisplatin-induced toxicity preincubated for 2 hrs followed by cisplatin challenge for 24 hrs by MTT assay | Sus scrofa | 7 | ALA3734678 | cell-based format | Scientific Literature | |
11. | ALA3738861 | Functional | Renoprotective activity in pig LLC-PK1 cells assessed as reduction in cisplatin-induced toxicity at 250 uM preincubated for 2 hrs followed by cisplatin challenge for 24 hrs by MTT assay | Sus scrofa | 4 | ALA3734678 | cell-based format | Scientific Literature | |
12. | ALA3745220 | Functional | Cytotoxicity against human 518A2 cells after 96 hrs by SRB assay | Homo sapiens | 45 | ALA3739286 | cell-based format | Scientific Literature | |
13. | ALA3745221 | Functional | Cytotoxicity against human A2780 cells after 96 hrs by SRB assay | Homo sapiens | 45 | ALA3739286 | cell-based format | Scientific Literature | |
14. | ALA3745222 | Functional | Cytotoxicity against human A549 cells after 96 hrs by SRB assay | Homo sapiens | 45 | ALA3739286 | cell-based format | Scientific Literature | |
15. | ALA3745223 | Functional | Cytotoxicity against human MCF7 cells after 96 hrs by SRB assay | Homo sapiens | 45 | ALA3739286 | cell-based format | Scientific Literature | |
16. | ALA3745224 | ADME | Cytotoxicity against mouse NIH/3T3 cells after 96 hrs by SRB assay | Mus musculus | 45 | ALA3739286 | cell-based format | Scientific Literature | |
17. | ALA3800826 | Functional | Cytotoxicity against human 518A2 cells after 96 hrs by SRB assay | Homo sapiens | 19 | ALA3797123 | cell-based format | Scientific Literature | |
18. | ALA3800827 | Functional | Cytotoxicity against human A2780 cells after 96 hrs by SRB assay | Homo sapiens | 19 | ALA3797123 | cell-based format | Scientific Literature | |
19. | ALA3800828 | Functional | Cytotoxicity against human HT-29 cells after 96 hrs by SRB assay | Homo sapiens | 19 | ALA3797123 | cell-based format | Scientific Literature | |
20. | ALA3800829 | Functional | Cytotoxicity against human MCF7 cells after 96 hrs by SRB assay | Homo sapiens | 19 | ALA3797123 | cell-based format | Scientific Literature |