# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1099853 | F | Antiviral activity against SFV infected in BHK cells assessed as surviving virus fraction at 50 uM after 14 hrs by luciferase reporter gene assay | Semliki Forest virus | 51 | organism-based format | Scientific Literature | ||
2. | ALA1099854 | F | Antiviral activity against SFV infected in BHK cells after 14 hrs by luciferase reporter gene assay | Semliki Forest virus | 21 | organism-based format | Scientific Literature | ||
3. | ALA1099856 | A | Cytotoxicity against human HuH7 cells assessed as cell viability at 50 uM after 24 hrs | Homo sapiens | 51 | cell-based format | Scientific Literature | ||
4. | ALA1099857 | A | Cytotoxicity against human HuH7 cells assessed as cell viability at 500 uM after 24 hrs | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
5. | ALA3738851 | F | Renoprotective activity in pig LLC-PK1 cells assessed as reduction in cisplatin-induced toxicity at 125 uM preincubated for 2 hrs followed by cisplatin challenge for 24 hrs by MTT assay | Sus scrofa | 4 | cell-based format | Scientific Literature | ||
6. | ALA3738852 | F | Renoprotective activity in pig LLC-PK1 cells assessed as reduction in cisplatin-induced cell shrank at 125 uM preincubated for 2 hrs followed by cisplatin challenge for 24 hrs by phase-contrast microscopic analysis | Sus scrofa | 4 | cell-based format | Scientific Literature | ||
7. | ALA3738853 | F | Renoprotective activity in pig LLC-PK1 cells assessed as reduction in cisplatin-induced progressive condensation at 125 uM preincubated for 2 hrs followed by cisplatin challenge for 24 hrs by phase-contrast microscopic analysis | Sus scrofa | 4 | cell-based format | Scientific Literature | ||
8. | ALA3738854 | F | Renoprotective activity in pig LLC-PK1 cells assessed as reduction in cisplatin-induced nucleus break-up at 125 uM preincubated for 2 hrs followed by cisplatin challenge for 24 hrs by phase-contrast microscopic analysis | Sus scrofa | 4 | cell-based format | Scientific Literature | ||
9. | ALA3738855 | F | Renoprotective activity against cisplatin induced toxicity in pig LLC-PK1 cells assessed as reduction in apoptotic cells at 125 uM preincubated for 2 hrs followed by cisplatin challenge for 24 hrs annexin-V-FITC and propidium iodide staining based flow cytometry | Sus scrofa | 4 | cell-based format | Scientific Literature | ||
10. | ALA3738856 | B | Inhibition of cisplatin-induced JNK phosphorylation in pig LLC-PK1 cells at 125 uM preincubated for 2 hrs followed by cisplatin challenge for 24 hrs by western blot analysis | Sus scrofa | 4 | cell-based format | Scientific Literature | ||
11. | ALA3738857 | B | Inhibition of cisplatin-induced ERK phosphorylation in pig LLC-PK1 cells at 125 uM preincubated for 2 hrs followed by cisplatin challenge for 24 hrs by western blot analysis | Sus scrofa | 4 | cell-based format | Scientific Literature | ||
12. | ALA3738858 | B | Inhibition of cisplatin-induced p38 phosphorylation in pig LLC-PK1 cells at 125 uM preincubated for 2 hrs followed by cisplatin challenge for 24 hrs by western blot analysis | Sus scrofa | 4 | cell-based format | Scientific Literature | ||
13. | ALA3738859 | F | Renoprotective activity in pig LLC-PK1 cells assessed as inhibition of cisplatin-induced cleaved caspase-3 expression at 125 uM preincubated for 2 hrs followed by cisplatin challenge for 24 hrs by western blot analysis | Sus scrofa | 4 | cell-based format | Scientific Literature | ||
14. | ALA3738860 | F | Renoprotective activity in pig LLC-PK1 cells assessed as reduction in cisplatin-induced toxicity preincubated for 2 hrs followed by cisplatin challenge for 24 hrs by MTT assay | Sus scrofa | 7 | cell-based format | Scientific Literature | ||
15. | ALA3738861 | F | Renoprotective activity in pig LLC-PK1 cells assessed as reduction in cisplatin-induced toxicity at 250 uM preincubated for 2 hrs followed by cisplatin challenge for 24 hrs by MTT assay | Sus scrofa | 4 | cell-based format | Scientific Literature | ||
16. | ALA3745220 | F | Cytotoxicity against human 518A2 cells after 96 hrs by SRB assay | Homo sapiens | 45 | cell-based format | Scientific Literature | ||
17. | ALA3745221 | F | Cytotoxicity against human A2780 cells after 96 hrs by SRB assay | Homo sapiens | 45 | cell-based format | Scientific Literature | ||
18. | ALA3745222 | F | Cytotoxicity against human A549 cells after 96 hrs by SRB assay | Homo sapiens | 45 | cell-based format | Scientific Literature | ||
19. | ALA3745223 | F | Cytotoxicity against human MCF7 cells after 96 hrs by SRB assay | Homo sapiens | 45 | cell-based format | Scientific Literature | ||
20. | ALA3745224 | A | Cytotoxicity against mouse NIH/3T3 cells after 96 hrs by SRB assay | Mus musculus | 45 | cell-based format | Scientific Literature |