# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1099853 | F | Antiviral activity against SFV infected in BHK cells assessed as surviving virus fraction at 50 uM after 14 hrs by luciferase reporter gene assay | Semliki Forest virus | 51 | organism-based format | Scientific Literature | ||
2. | ALA1099856 | A | Cytotoxicity against human HuH7 cells assessed as cell viability at 50 uM after 24 hrs | Homo sapiens | 51 | cell-based format | Scientific Literature | ||
3. | ALA3385369 | F | Antiparasitic activity against Leishmania braziliensis assessed as inhibition of growth after 72 hrs | Leishmania braziliensis | 4 | organism-based format | Scientific Literature | ||
4. | ALA3385370 | F | Antiparasitic activity against Leishmania braziliensis assessed as inhibition of growth after 72 hrs at 10 uM | Leishmania braziliensis | 4 | organism-based format | Scientific Literature | ||
5. | ALA3385371 | A | Cytotoxicity against mouse J774.A1 cells | Mus musculus | 4 | cell-based format | Scientific Literature | ||
6. | ALA3385372 | T | Selectivity index, ratio of IC50 for mouse J774.A1 cells to IC50 for Leishmania braziliensis | 4 | cell-based format | Scientific Literature | |||
7. | ALA3385373 | F | Leishmanicidal activity against Leishmania braziliensis assessed as dead cells at 10'-6 M after 30 mins by chemotactic assay | Leishmania braziliensis | 4 | organism-based format | Scientific Literature | ||
8. | ALA3385375 | F | Leishmanicidal activity against Leishmania braziliensis assessed as reduction in parasite migration at 10'-6 M after 30 mins by chemotactic assay | Leishmania braziliensis | 2 | organism-based format | Scientific Literature | ||
9. | ALA3801297 | F | Antiinflammatory activity in mouse J774 cells assessed as inhibition of LPS-induced nitric oxide production measured as remaining nitric oxide levels at 10 uM by Griess assay | Mus musculus | 18 | cell-based format | Scientific Literature | ||
10. | ALA3801298 | F | Antiinflammatory activity in mouse J774 cells assessed as inhibition of LPS-induced iNOS expression measured as remaining protein levels at 10 uM after 24 hrs by Western blot analysis | Mus musculus | 18 | cell-based format | Scientific Literature | ||
11. | ALA3801299 | F | Antiinflammatory activity against mouse J774 cells assessed as inhibition of LPS-induced COX-2 expression measured as remaining protein levels at 10 uM after 24 hrs by Western blot analysis | Mus musculus | 18 | cell-based format | Scientific Literature | ||
12. | ALA3801300 | F | Antiinflammatory activity against mouse J774 cells assessed as inhibition of LPS-induced IL-6 production measured as remaining IL-6 levels at 10 uM after 24 hrs by ELISA | Mus musculus | 18 | cell-based format | Scientific Literature | ||
13. | ALA3801301 | F | Antiinflammatory activity against mouse J774 cells assessed as inhibition of LPS-induced MCP-1 production measured as remaining MCP-1 levels at 10 uM after 24 hrs by ELISA | Mus musculus | 18 | cell-based format | Scientific Literature | ||
14. | ALA3801302 | F | Antiinflammatory activity against mouse J774 cells assessed as inhibition of LPS-induced iNOS expression after 24 hrs by Western blot analysis | Mus musculus | 3 | cell-based format | Scientific Literature | ||
15. | ALA3801303 | F | Inhibition of LPS-induced iNOS mRNA levels in mouse J774 cells after 6 hrs by qRT-PCR method | Mus musculus | 3 | cell-based format | Scientific Literature | ||
16. | ALA5152412 | B | Inhibition of HBV subgenotype D3 [3H]-myr-preS1 (2 to 48 residues) peptide binding to human NTCP in HEK293 cells preincubated for 5 mins followed by substrate addition and measured after 10 mins using by microplate scintillation counter analysis | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
17. | ALA5152413 | B | Selectivity index, ratio of IC50 for inhibition of human NTCP mediated TCA uptake in HEK293 cells overexpressing NTCP to IC50 for inhibition of HBV subgenotype D3 [3H]-myr-preS1 (2 to 48 residues) peptide binding to human NTCP in HEK293 cells overexpressing NTCP | Homo sapiens | 9 | cell-based format | Scientific Literature |