# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1108688 | Toxicity | Toxicity in mouse Colon 38 cells xenografted C57BL/6 mouse assessed as mortality at 3 mg/kg, iv administered as a single dose | Mus musculus | 14 | ALA1154840 | organism-based format | Scientific Literature | |
2. | ALA1108689 | Binding | Inhibition of HCV NS3/4A protease by quantitative RT-PCR | Hepatitis C virus | 16 | ALA1154840 | assay format | Scientific Literature | |
3. | ALA1108690 | Functional | Antiviral activity against HCV infected in hamster brain assessed as inhibition of subacute sclerosing panencephalitis dosed intracranially by HPLC | Hepacivirus hominis | 16 | ALA1154840 | organism-based format | Scientific Literature | |
4. | ALA1108691 | Functional | Antioxidant activity against DPPH radical scavenging activity after 30 mins by ELISA | 16 | ALA1154840 | assay format | Scientific Literature | ||
5. | ALA1108692 | Functional | Antioxidant activity against peroxynitrite-induced tyrosine nitration after 15 mins by HPLC | 16 | ALA1154840 | assay format | Scientific Literature | ||
6. | ALA1108693 | Functional | Growth inhibition of mouse Colon 38 cells after 72 hrs by sulforhodamine B assay relative to etoposide | Mus musculus | 15 | ALA1154840 | cell-based format | Scientific Literature | |
7. | ALA1108694 | Functional | Antitumor activity against mouse Colon 38 cells xenografted in C57BL/6 mouse assessed as tumor volume at 3 mg/kg, iv administered as a single dose | Mus musculus | 14 | ALA1154840 | organism-based format | Scientific Literature | |
8. | ALA1108695 | Toxicity | Toxicity in mouse Colon 38 cells xenografted C57BL/6 mouse assessed as body weight change at 3 mg/kg, iv administered as a single dose | Mus musculus | 14 | ALA1154840 | organism-based format | Scientific Literature | |
9. | ALA1108697 | Binding | Inhibition of mouse DNA topoisomerase 2 assessed as relaxation of supercoiled pBR322 plasmid DNA after 1 hr by electrophoresis relative to etoposide | Mus musculus | 15 | ALA1154840 | single protein format | Scientific Literature | |
10. | ALA4148665 | Binding | Inhibition of biotinylated-H4KAc4 binding to human His6-tagged CBP (R1081 to G1197 residues) expressed in Escherichia coli BL21(DE3) after 2.5 hrs by luminescence-based AlphaScreen assay | Homo sapiens | 61 | ALA4145544 | assay format | Scientific Literature | |
11. | ALA4148666 | Binding | Inhibition of biotinylated-H4KAc4 binding to human His6-tagged BRD4 bromodomain-1 (N44 to E168 residues) expressed in Escherichia coli BL21(DE3) at 50 uM after 2.5 hrs by luminescence-based AlphaScreen assay relative to control | Homo sapiens | 14 | ALA4145544 | assay format | Scientific Literature | |
12. | ALA4148667 | Binding | Inhibition of biotinylated-H4KAc4 binding to human His6-tagged BAZ2B (S1858 to S1972 residues) expressed in Escherichia coli BL21(DE3) at 50 uM after 2.5 hrs by luminescence-based AlphaScreen assay relative to control | Homo sapiens | 14 | ALA4145544 | assay format | Scientific Literature | |
13. | ALA4148668 | Binding | Inhibition of biotinylated-H4KAc4 binding to human His6-tagged ATAD2 expressed in Escherichia coli BL21(DE3) at 50 uM after 2.5 hrs by luminescence-based AlphaScreen assay relative to control | Homo sapiens | 14 | ALA4145544 | assay format | Scientific Literature |