| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1099785 | F | Agonist activity at rat alpha3beta4 nAChR expressed in HEK cells assessed as membrane depolarization after 1 hr by HPLC based fluorescence assay | Rattus norvegicus | 2 | ALA1155436 | cell-based format | Scientific Literature | |
| 2. | ALA1099786 | F | Agonist activity at human alpha3beta4 nAChR in human IMR32 cells assessed as membrane depolarization after 1 hr by HPLC based fluorescence assay | Homo sapiens | 2 | ALA1155436 | cell-based format | Scientific Literature | |
| 3. | ALA1099787 | F | Agonist activity at human alpha3beta4 nAChR in human SH-SY5Y cells assessed as membrane depolarization after 1 hr by HPLC based fluorescence assay | Homo sapiens | 2 | ALA1155436 | cell-based format | Scientific Literature | |
| 4. | ALA1099788 | F | Agonist activity at rat alpha3beta4 nAChR expressed in HEK cells assessed as elevation of intracellular calcium after 1 hr by HPLC based fluorescence assay | Rattus norvegicus | 2 | ALA1155436 | cell-based format | Scientific Literature | |
| 5. | ALA1099789 | F | Agonist activity at rat alpha4beta2 nAChR expressed in HEK cells assessed as membrane depolarization after 1 hr by HPLC based fluorescence assay | Rattus norvegicus | 1 | ALA1155436 | cell-based format | Scientific Literature | |
| 6. | ALA1099790 | F | Agonist activity at rat alpha4beta4 nAChR expressed in HEK cells assessed as membrane depolarization after 1 hr by HPLC based fluorescence assay | Rattus norvegicus | 1 | ALA1155436 | cell-based format | Scientific Literature | |
| 7. | ALA1099791 | F | Agonist activity at human alpha-1-beta-1-gamma-delta nAChR expressed in human TE671 cells assessed as membrane depolarization after 1 hr by HPLC based fluorescence assay | Homo sapiens | 1 | ALA1155436 | cell-based format | Scientific Literature | |
| 8. | ALA1099792 | F | Agonist activity at human alpha4beta2 nAChR expressed in human K177 cells assessed as membrane depolarization after 1 hr by HPLC based fluorescence assay | Homo sapiens | 1 | ALA1155436 | cell-based format | Scientific Literature | |
| 9. | ALA4256520 | B | Displacement of [3H]epibatidine from alpha3beta4 nAChR (unknown origin) expressed in HEK cell membranes after 4 hrs by liquid scintillation counting method | Homo sapiens | 5 | ALA4251743 | cell-based format | Scientific Literature | |
| 10. | ALA4256521 | B | Displacement of [3H]epibatidine from alpha4beta2 nAChR (unknown origin) expressed in HEK cell membranes after 4 hrs by liquid scintillation counting method | Homo sapiens | 5 | ALA4251743 | cell-based format | Scientific Literature | |
| 11. | ALA4256522 | B | Displacement of [3H]epibatidine from alpha7 nAChR (unknown origin) expressed in HEK cell membranes after 4 hrs by liquid scintillation counting method | Homo sapiens | 5 | ALA4251743 | cell-based format | Scientific Literature | |
| 12. | ALA4256523 | B | Selectivity ratio of Ki for displacement of [3H]epibatidine from alpha3beta4 nAChR (unknown origin) expressed in HEK cell membranes to Ki for displacement of [3H]epibatidine from alpha4beta2 nAChR (unknown origin) expressed in HEK cell membranes | Homo sapiens | 5 | ALA4251743 | cell-based format | Scientific Literature | |
| 13. | ALA4256526 | B | Displacement of [3H]epibatidine from rat forebrain nAChR after 4 hrs by liquid scintillation counting method | Rattus norvegicus | 5 | ALA4251743 | assay format | Scientific Literature | |
| 14. | ALA4256528 | B | Agonist activity at rat alpha3beta4 nAChR by cell-based rubidium flux assay | Rattus norvegicus | 5 | ALA4251743 | cell-based format | Scientific Literature | |
| 15. | ALA4256529 | B | Agonist activity at rat alpha3beta4 nAChR by cell-based rubidium flux assay relative to 100 uM nicotine | Rattus norvegicus | 5 | ALA4251743 | cell-based format | Scientific Literature | |
| 16. | ALA4256530 | B | Agonist activity at human alpha4beta2 nAChR by cell-based rubidium flux assay | Homo sapiens | 5 | ALA4251743 | cell-based format | Scientific Literature | |
| 17. | ALA4256531 | B | Agonist activity at human alpha4beta2 nAChR by cell-based rubidium flux assay relative to 100 uM nicotine | Homo sapiens | 5 | ALA4251743 | cell-based format | Scientific Literature | |
| 18. | ALA4256532 | B | Selectivity ratio of EC50 for agonist activity at rat alpha3beta4 nAChR (unknown origin) to EC50 for agonist activity at alpha4beta2 nAChR (unknown origin) | Homo sapiens | 5 | ALA4251743 | assay format | Scientific Literature | |
| 19. | ALA4256533 | B | Agonist activity at rat alpha3beta2 expressed in Xenopus oocytes at -60 mV holding potential by electrophysiology method | Rattus norvegicus | 4 | ALA4251743 | cell-based format | Scientific Literature | |
| 20. | ALA4256534 | B | Agonist activity at rat alpha3beta2 expressed in Xenopus oocytes at -60 mV holding potential by electrophysiology method relative to acetylcholine | Rattus norvegicus | 3 | ALA4251743 | cell-based format | Scientific Literature |
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