The store will not work correctly when cookies are disabled.
The page will load shortly, Thanks for your patience!
| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source |
| 1. | ALA1100948 | B | Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of sodium-dependent methyl-alpha-D-[U-14C]glucopyranoside uptake after 2 hrs | Homo sapiens | 13 | | cell-based format | Scientific Literature |
| 2. | ALA1101142 | B | Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of sodium-dependent methyl-alpha-D-[U-14C]glucopyranoside uptake after 2 hrs | Homo sapiens | 23 | | cell-based format | Scientific Literature |
| 3. | ALA1101144 | A | Clearance in Sprague-Dawley rat at 2 mg/kg, iv | Rattus norvegicus | 2 | | organism-based format | Scientific Literature |
| 4. | ALA1101146 | A | Volume of distribution at steady state in Sprague-Dawley rat at 2 mg/kg, iv | Rattus norvegicus | 2 | | organism-based format | Scientific Literature |
| 5. | ALA1101148 | A | Half life in Sprague-Dawley rat at 2 mg/kg, iv | Rattus norvegicus | 2 | | organism-based format | Scientific Literature |
| 6. | ALA1101150 | A | Oral bioavailability in Sprague-Dawley rat at 5 mg/kg | Rattus norvegicus | 2 | | organism-based format | Scientific Literature |
| 7. | ALA1101848 | F | Antidiabetic activity in Sprague-Dawley rat assessed as maximum urinary glucose excretion at 60 mg/kg, po over 24 hrs measured per 200 g body weight | Rattus norvegicus | 1 | | organism-based format | Scientific Literature |
| 8. | ALA1771928 | A | Hepatic clearance in Sprague-Dawley rat at 2 mg/kg, iv | Rattus norvegicus | 1 | | organism-based format | Scientific Literature |
| 9. | ALA1771929 | A | Volume of distribution at steady state in Sprague-Dawley rat at 2 mg/kg, iv | Rattus norvegicus | 5 | | organism-based format | Scientific Literature |
| 10. | ALA1771930 | A | Half life in Sprague-Dawley rat at 2 mg/kg, iv | Rattus norvegicus | 5 | | organism-based format | Scientific Literature |
| 11. | ALA1772492 | P | Lipophilicity, log D of the compound | | 10 | | small-molecule physicochemical format | Scientific Literature |
| 12. | ALA1772493 | B | Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of methyl alpha-D-glucopyranoside uptake after 1 hr | Homo sapiens | 7 | | cell-based format | Scientific Literature |
| 13. | ALA1772494 | B | Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of methyl alpha-D-glucopyranoside uptake after 1 hr | Homo sapiens | 7 | | cell-based format | Scientific Literature |
| 14. | ALA1772497 | A | Apparent intrinsic clearance in human liver microsomes assessed per mg of protein | Homo sapiens | 9 | | microsome format | Scientific Literature |
| 15. | ALA1772498 | A | Apparent intrinsic clearance in human hepatocytes assessed per million of cells | Homo sapiens | 9 | | cell-based format | Scientific Literature |
| 16. | ALA1772501 | A | Plasma clearance in Sprague-Dawley rat at 2 mg/kg, iv | Rattus norvegicus | 5 | | organism-based format | Scientific Literature |
| 17. | ALA1772502 | A | Renal clearance in Sprague-Dawley rat at 2 mg/kg, iv | Rattus norvegicus | 1 | | organism-based format | Scientific Literature |
| 18. | ALA4376708 | A | Fraction unbound in Wistar Han rat plasma at 2 uM incubated for 6 hrs by equilibrium dialysis method | Rattus norvegicus | 56 | | cell-free format | Scientific Literature |
| 19. | ALA4376709 | A | Fraction unbound in Wistar Han rat white adipose tissue at 2 uM incubated for 6 hrs by equilibrium dialysis method | Rattus norvegicus | 56 | | tissue-based format | Scientific Literature |
| 20. | ALA4376710 | A | Fraction unbound in Wistar Han rat brain at 2 uM incubated for 6 hrs by equilibrium dialysis method | Rattus norvegicus | 56 | | tissue-based format | Scientific Literature |