| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3537288 | ADME | Fraction unbound in Sprague-Dawley rat brain homogenates at 5 uM by equilibrium dialysis analysis | Rattus norvegicus | 56 | ALA3525927 | tissue-based format | Scientific Literature | |
| 2. | ALA3537289 | ADME | Unbound volume of distribution in Sprague-Dawley rat brain slices at 100 nM after 5 hrs | Rattus norvegicus | 56 | ALA3525927 | tissue-based format | Scientific Literature | |
| 3. | ALA3537290 | ADME | Unbound drug partitioning coefficient, Kp of the compound assessed as ratio of unbound concentration in Sprague-Dawley rat brain to unbound concentration in plasma | Rattus norvegicus | 56 | ALA3525927 | cell-free format | Scientific Literature | |
| 4. | ALA3532944 | Physicochemical | Dissociation constant, pKa of the acidic compound by capillary electrophoresis-mass spectrometry analysis | 42 | ALA3525927 | small-molecule physicochemical format | Scientific Literature | ||
| 5. | ALA3529441 | Physicochemical | Dissociation constant, pKa of the compound | 73 | ALA3526022 | small-molecule physicochemical format | Scientific Literature | ||
| 6. | ALA618310 | ADME | Unbound fraction (plasma) | Homo sapiens | 120 | ALA1148291 | cell-free format | Scientific Literature | |
| 7. | ALA624569 | ADME | Observed volume of distribution | Homo sapiens | 120 | ALA1148291 | organism-based format | Scientific Literature | |
| 8. | ALA627543 | Physicochemical | Log D of compound; LogD at pH 7.4 | 9 | ALA1129378 | small-molecule physicochemical format | Scientific Literature | ||
| 9. | ALA630211 | Physicochemical | Partition coefficient of Zwitterion (logD) | 9 | ALA1129378 | small-molecule physicochemical format | Scientific Literature | ||
| 10. | ALA630216 | Physicochemical | Partition coefficient of cation (logD) | 8 | ALA1129378 | small-molecule physicochemical format | Scientific Literature | ||
| 11. | ALA631962 | Physicochemical | Aqueous solubility | 148 | ALA1132890 | small-molecule physicochemical format | Scientific Literature | ||
| 12. | ALA631377 | Physicochemical | Partition coefficient (logD7.4) | 90 | ALA1134540 | small-molecule physicochemical format | Scientific Literature | ||
| 13. | ALA633649 | ADME | Delta logD (logD6.5 - logD7.4) | 111 | ALA1133765 | assay format | Scientific Literature | ||
| 14. | ALA858450 | Physicochemical | Partition coefficient (logP) | 30 | ALA1124051 | small-molecule physicochemical format | Scientific Literature | ||
| 15. | ALA635314 | Physicochemical | Amine pKa of compound | 9 | ALA1129378 | small-molecule physicochemical format | Scientific Literature | ||
| 16. | ALA634283 | Physicochemical | Partition coefficient (logD6.5) | 114 | ALA1133765 | small-molecule physicochemical format | Scientific Literature | ||
| 17. | ALA633292 | Physicochemical | Ionization constant (pKa) | 80 | ALA1148291 | small-molecule physicochemical format | Scientific Literature | ||
| 18. | ALA645153 | Physicochemical | Ionization constant (pKa) | 204 | ALA1133765 | small-molecule physicochemical format | Scientific Literature | ||
| 19. | ALA633098 | ADME | Oral bioavailability in human | Homo sapiens | 184 | ALA1133765 | organism-based format | Scientific Literature | |
| 20. | ALA665723 | ADME | Inhibition of MAMC O-dealkylation mediated by rat Cytochrome P450 2D1 expressed in Saccharomyces cerevisiae | Rattus norvegicus | 9 | ALA1145023 | assay format | Scientific Literature |
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