| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1111448 | Binding | Displacement of [3H]flumazenil from GABAA alpha-5-beta-3-gamma-2 receptor | 15 | ALA1154267 | protein complex format | Scientific Literature | ||
| 2. | ALA1111449 | Binding | Displacement of [3H]flumazenil from GABAA alpha-1-beta-3-gamma-2 receptor | 9 | ALA1154267 | protein complex format | Scientific Literature | ||
| 3. | ALA1111450 | Binding | Displacement of [3H]flumazenil from GABAA alpha-2-beta-3-gamma-2 receptor | 9 | ALA1154267 | protein complex format | Scientific Literature | ||
| 4. | ALA1111451 | Binding | Displacement of [3H]flumazenil from GABAA alpha-3-beta-3-gamma-2 receptor | 9 | ALA1154267 | protein complex format | Scientific Literature | ||
| 5. | ALA1111452 | Functional | Inverse agonist activity at GABAA alpha-5-beta-3-gamma-2 receptor assessed as modulation of GABA-induced chloride ion flux by electrophysiology assay relative to GABA | 15 | ALA1154267 | assay format | Scientific Literature | ||
| 6. | ALA1111459 | Physicochemical | Solubility of the compound | 3 | ALA1154267 | small-molecule physicochemical format | Scientific Literature | ||
| 7. | ALA1111460 | Physicochemical | Lipophilicity, log D at pH 7.4 | 3 | ALA1154267 | small-molecule physicochemical format | Scientific Literature | ||
| 8. | ALA1111461 | ADME | Permeability by PAMPA | 3 | ALA1154267 | assay format | Scientific Literature | ||
| 9. | ALA1111462 | ADME | Clearance in rat liver microsomes | Rattus norvegicus | 3 | ALA1154267 | microsome format | Scientific Literature | |
| 10. | ALA1111463 | ADME | Clearance in human liver microsomes | Homo sapiens | 3 | ALA1154267 | microsome format | Scientific Literature | |
| 11. | ALA1111464 | ADME | Half life in rat | Rattus norvegicus | 3 | ALA1154267 | organism-based format | Scientific Literature | |
| 12. | ALA1111465 | ADME | Clearance in rat | Rattus norvegicus | 3 | ALA1154267 | organism-based format | Scientific Literature | |
| 13. | ALA1111466 | ADME | Volume of distribution at steady state in rat | Rattus norvegicus | 3 | ALA1154267 | organism-based format | Scientific Literature | |
| 14. | ALA1111467 | ADME | Oral bioavailability in rat | Rattus norvegicus | 3 | ALA1154267 | organism-based format | Scientific Literature | |
| 15. | ALA1111468 | ADME | Ratio of drug level in brain to plasma in rat | Rattus norvegicus | 3 | ALA1154267 | organism-based format | Scientific Literature | |
| 16. | ALA1111469 | Functional | Behavioral effect in Lister hooded rat assessed as reversal of Scopolamine-induced impairment of working memory at 1 to 3 mg/kg, ip administered 30 mins before Scopolamine challenge by delayed match to position test | Rattus norvegicus | 1 | ALA1154267 | organism-based format | Scientific Literature | |
| 17. | ALA1111471 | Functional | Behavioral effect in Lister hooded rat assessed as inhibition of scopolamine-induced impairment of working memory at 1 to 3 mg/kg, po after 30 mins by delayed match to position test | Rattus norvegicus | 1 | ALA1154267 | organism-based format | Scientific Literature |
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