# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1106726 | B | Inhibition of human 17beta-HSD5 expressed in HEK293 cells assessed as inhibition of conversion of [14C]4-androstene-3,17-dione to [14C]testosterone at 0.3 uM after 20 hrs | Homo sapiens | 2 | ALA1154295 | cell-based format | Scientific Literature | |
2. | ALA1106727 | B | Inhibition of human 17beta-HSD1 expressed in HEK293 cells assessed as inhibition of reduction of [14C]estrone into [14C]estradiol at 0.1 uM | Homo sapiens | 2 | ALA1154295 | cell-based format | Scientific Literature | |
3. | ALA1106728 | B | Inhibition of human 5alpha reductase 1 expressed in HEK293 cells assessed as inhibition of conversion of [14C]4-androstene-3,17-dione to [14C]5R-androstane-3,17-dione at 0.3 uM after 1 hr | Homo sapiens | 2 | ALA1154295 | cell-based format | Scientific Literature | |
4. | ALA1106729 | B | Inhibition of human 5alpha reductase 2 expressed in HEK293 cells assessed as inhibition of conversion of [14C]4-androstene-3,17-dione to [14C]5R-androstane-3,17-dione at 0.3 uM after 3 hrs | Homo sapiens | 3 | ALA1154295 | cell-based format | Scientific Literature | |
5. | ALA1106731 | B | Inhibition of human 17beta-HSD7 expressed in HEK293 cells assessed as inhibition of reduction of [14C]dihydrotestosterone into [14C]5alpha-androstane-3beta,17beta-diol at 3 uM after 18 hrs | Homo sapiens | 10 | ALA1154295 | cell-based format | Scientific Literature |