# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1113189 | Binding | Inhibition of Sprague-Dawley rat lens aldose reductase by spectrofluorimetry | Rattus norvegicus | 19 | ALA1154220 | single protein format | Scientific Literature | |
2. | ALA1113190 | Physicochemical | Inhibition of advanced glycation end product formation after 14 day in phosphate buffer at pH7.4 by spectrofluorimetry | 19 | ALA1154220 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA1115749 | Functional | Antiinflammatory activity against mouse N9 cells assessed as inhibition of LPS-induced nitric oxide production at 1 uM after 48 hrs by Griess reaction relative to control | Mus musculus | 25 | ALA1154236 | cell-based format | Scientific Literature | |
4. | ALA1115750 | Functional | Antiinflammatory activity against mouse N9 cells assessed as inhibition of LPS-induced nitric oxide production at 3 uM after 48 hrs by Griess reaction relative to control | Mus musculus | 25 | ALA1154236 | cell-based format | Scientific Literature | |
5. | ALA1115751 | Functional | Antiinflammatory activity against mouse N9 cells assessed as inhibition of LPS-induced nitric oxide production at 10 uM after 48 hrs by Griess reaction relative to control | Mus musculus | 25 | ALA1154236 | cell-based format | Scientific Literature | |
6. | ALA1115752 | Functional | Antiinflammatory activity against mouse N9 cells assessed as inhibition of LPS-induced nitric oxide production at 30 uM after 48 hrs by Griess reaction relative to control | Mus musculus | 25 | ALA1154236 | cell-based format | Scientific Literature | |
7. | ALA1115753 | ADME | Cytotoxicity against LPS-stimulated mouse N9 cells at 1 to 30 uM after 48 hrs by MTT assay | Mus musculus | 4 | ALA1154236 | cell-based format | Scientific Literature | |
8. | ALA2216091 | ADME | Cytotoxicity against mouse RAW264.7 cells after 24 hrs | Mus musculus | 27 | ALA2203236 | cell-based format | Scientific Literature | |
9. | ALA2216092 | Functional | Inhibition of LPS-induced NO production in mouse RAW264.7 cells after 24 hrs by Griess reaction | Mus musculus | 27 | ALA2203236 | cell-based format | Scientific Literature | |
10. | ALA3108376 | Functional | Anticomplement activity in sheep erythrocytes in C9-depleted serum assessed as inhibition of hemolysis by classical pathway at 0.54 mM after 30 mins compound treated in normal human serum | Ovis aries | 1 | ALA3102746 | cell-based format | Scientific Literature | |
11. | ALA3108377 | Functional | Anticomplement activity in sheep erythrocytes in C5-depleted serum assessed as inhibition of hemolysis by classical pathway at 0.54 mM after 30 mins compound treated in normal human serum | Ovis aries | 1 | ALA3102746 | cell-based format | Scientific Literature | |
12. | ALA3108378 | Functional | Anticomplement activity in sheep erythrocytes in C3-depleted serum assessed as inhibition of hemolysis by classical pathway at 0.54 mM after 30 mins compound treated in normal human serum | Ovis aries | 1 | ALA3102746 | cell-based format | Scientific Literature | |
13. | ALA3108379 | Functional | Anticomplement activity in sheep erythrocytes in C1q-depleted serum assessed as inhibition of hemolysis by classical pathway at 0.54 mM after 30 mins compound treated in normal human serum | Ovis aries | 1 | ALA3102746 | cell-based format | Scientific Literature | |
14. | ALA3106381 | Functional | Anticomplement activity in New Zealand White rabbit erythrocytes assessed as concentration required for 50% hemolytic inhibition by alternative pathway after 30 mins | Oryctolagus cuniculus | 23 | ALA3102746 | cell-based format | Scientific Literature | |
15. | ALA3106382 | Functional | Anticomplement activity in sheep erythrocytes assessed as concentration required for 50% hemolytic inhibition by classical pathway after 30 mins by spectrophotometry | Ovis aries | 23 | ALA3102746 | cell-based format | Scientific Literature |