# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA626439 | P | Lipophilicity (Rm) (liquid chromatography) | 40 | ALA1122747 | small-molecule physicochemical format | Scientific Literature | ||
2. | ALA634152 | A | Susceptibility to thiolytic cleavage: T1/2 in presence of excess 2-mercaptoethanol | 48 | ALA1121904 | assay format | Scientific Literature | ||
3. | ALA633895 | P | Ionization constant (pKa) | 181 | ALA1122023 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA635217 | P | Ionisation constant (pKa) | 48 | ALA1121904 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA633379 | A | Binding affinity towards poly[d(A-T)] (fluorometric method) | 40 | ALA1122747 | assay format | Scientific Literature | ||
6. | ALA666211 | B | Association constant measured for binding towards poly[d(A-T)] of DNA in calf thymus | Bos taurus | 48 | ALA1121904 | nucleic acid format | Scientific Literature | |
7. | ALA665220 | B | Binding constant (log K) for DNA binding by ethidium bromide displacement | Bos taurus | 55 | ALA1123442 | nucleic acid format | Scientific Literature | |
8. | ALA705840 | F | In vitro test for 50% reduction of cell number (of control) after 70 hr incubation with cultures of murine L1210 leukemia cells | Mus musculus | 40 | ALA1122747 | cell-based format | Scientific Literature | |
9. | ALA703726 | F | Drug concentration in mole/kg/day providing 50% extension of life in intraperitoneally implanted leukemia L1210 mice. | Mus musculus | 771 | ALA1122023 | cell-based format | Scientific Literature | |
10. | ALA740214 | A | LD10 in mice | Mus musculus | 48 | ALA1121904 | organism-based format | Scientific Literature | |
11. | ALA743080 | F | Molar dose providing 40 percent increase in the life span of leukemic mice | Mus musculus | 48 | ALA1121904 | organism-based format | Scientific Literature | |
12. | ALA753371 | F | Dose of drug needed to provide a percentage increase in life span of tumor-bearing mice in vivo of 50% compared to untreated controls after inoculation of 10e6 P388 leukemia cells; h=ILS of >50% could not be obtained at any dose level | Mus musculus | 14 | ALA1122747 | organism-based format | Scientific Literature | |
13. | ALA761069 | F | In vivo tumor cell selectivity (ILSmax values)for percentage increase in life span of treated animals over that of P388 tumor bearing untreated control animals | Mus musculus | 35 | ALA1122747 | organism-based format | Scientific Literature | |
14. | ALA761378 | F | In vivo inhibition of P388 in mice for optimal (highest nonacutely toxic) dose (OD) | Mus musculus | 40 | ALA1122747 | organism-based format | Scientific Literature | |
15. | ALA813896 | A | Compound concentration in mole/kg/day lethal to 10% of mice | Mus sp. | 771 | ALA1122023 | organism-based format | Scientific Literature |