| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1053700 | A | Cytotoxicity against human HepG2 cells assessed as cell survival at 5 uM after 24 hrs by MTT assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 2. | ALA1053701 | A | Cytotoxicity against human HepG2 cells assessed as cell survival at 10 uM after 24 hrs by MTT assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 3. | ALA1053702 | A | Cytotoxicity against human HepG2 cells assessed as cell survival at 20 uM after 24 hrs by MTT assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 4. | ALA1053703 | A | Cytotoxicity against human HepG2 cells assessed as cell survival at 100 uM after 24 hrs by MTT assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 5. | ALA1053704 | B | Induction of AMPK phosphorylation in human HepG2 cells at 10 uM by Western blot analysis in presence of 33 mM glucose | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 6. | ALA1053705 | B | Induction of GSK3-beta phosphorylation in human HepG2 cells at 10 uM by Western blot analysis in presence of 33 mM glucose | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 7. | ALA1054445 | F | Increase in glycogen synthesis in human HepG2 cells assessed as incorporation of [14C]glucose in to cellular glycogen pools at 10 uM after 60 mins in presence of 33 mM glucose | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 8. | ALA1054446 | F | Induction of glucose uptake in human HepG2 cells at 10 uM in presence of 33 mM 2-[14C]-DOG by scintillation counting | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 9. | ALA1113189 | B | Inhibition of Sprague-Dawley rat lens aldose reductase by spectrofluorimetry | Rattus norvegicus | 19 | single protein format | Scientific Literature | ||
| 10. | ALA1113190 | P | Inhibition of advanced glycation end product formation after 14 day in phosphate buffer at pH7.4 by spectrofluorimetry | 19 | small-molecule physicochemical format | Scientific Literature | |||
| 11. | ALA4702260 | B | Inhibition of CES2A1 in human liver microsomes using D-luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition and measured after 10 mins by fluorescence assay | Homo sapiens | 14 | microsome format | Scientific Literature | ||
| 12. | ALA4702261 | B | Inhibition of CES1A1 in human liver microsomes using D-luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition and measured after 10 mins by fluorescence assay | Homo sapiens | 9 | microsome format | Scientific Literature | ||
| 13. | ALA4702262 | B | Selectivity ratio of IC50 for inhibition of CES2A1 in human liver microsomes to IC50 for CES1A1 in human liver microsomes | Homo sapiens | 9 | microsome format | Scientific Literature |
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