# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1112746 | Binding | Inhibition of human complement factor B treated for 5 mins before addition of substrate Ac-SHLGLAR-pNA at pH 9.5 by chromogenic assay | Homo sapiens | 12 | ALA1156245 | single protein format | Scientific Literature | |
2. | ALA1113622 | Binding | Inhibition of human C3 convertase assessed as inhibition of C3a and C3b fragment production at pH 7.4 after 30 mins by SDS-PAGE using 7% (w/v) polyacrylamide gel | Homo sapiens | 2 | ALA1156245 | single protein format | Scientific Literature | |
3. | ALA1113623 | Binding | Inhibition of human C3 convertase assessed as inhibition of C3a and C3b fragment production at pH 7.4 after 30 mins by SDS-PAGE using 12% (w/v) polyacrylamide gel | Homo sapiens | 2 | ALA1156245 | single protein format | Scientific Literature | |
4. | ALA1113624 | Binding | Inhibition of human C3 convertase assessed as inhibition of C3a and C3b fragment production at pH 7.4 after 30 mins by SDS-PAGE | Homo sapiens | 2 | ALA1156245 | single protein format | Scientific Literature | |
5. | ALA1113626 | Binding | Inhibition of human alternative complement system-mediated membrane attack complex formation by ELISA | Homo sapiens | 3 | ALA1156245 | assay format | Scientific Literature | |
6. | ALA1113627 | Binding | Inhibition of alternative complement system-mediated hemolysis of rabbit erythrocytes assessed as haemoglobin release after 30 mins by UV/vis spectrophotometry | Oryctolagus cuniculus | 3 | ALA1156245 | assay format | Scientific Literature | |
7. | ALA1113628 | Binding | Ratio of Ac-SHLGLAR-H IC50 to compound IC50 for human complement factor B | Homo sapiens | 1 | ALA1156245 | single protein format | Scientific Literature |