| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1614459 | Functional | PUBCHEM_BIOASSAY: qHTS Assay for Lipid Storage Modulators in Drosophila S3 Cells. (Class of assay: confirmatory) | Drosophila | 88,408 | ALA1201862 | assay format | PubChem BioAssays | |
| 2. | ALA1614530 | Functional | PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] | Escherichia coli | 61,607 | ALA1201862 | assay format | PubChem BioAssays | |
| 3. | ALA1614337 | Functional | PUBCHEM_BIOASSAY: Confirmation Concentration-Response Assay for Activators of Human Reticulocyte Pyruvate Kinase. (Class of assay: confirmatory) [Related pubchem assays: 1751 ] | Homo sapiens | 47 | ALA1201862 | assay format | PubChem BioAssays | |
| 4. | ALA1613907 | Functional | PUBCHEM_BIOASSAY: Secondary assay for Activators of Human Pyruvate Kinase M2 isoform. (Class of assay: confirmatory) [Related pubchem assays: 1634, 1631 ] | Homo sapiens | 145 | ALA1201862 | assay format | PubChem BioAssays | |
| 5. | ALA1613914 | Functional | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) | Homo sapiens | 39,332 | ALA1201862 | assay format | PubChem BioAssays | |
| 6. | ALA1613954 | Functional | PUBCHEM_BIOASSAY: Confirmation Concentration-Response Assay for Activators of Human Liver Pyruvate Kinase. (Class of assay: confirmatory) [Related pubchem assays: 1751 ] | Homo sapiens | 33 | ALA1201862 | assay format | PubChem BioAssays | |
| 7. | ALA1613974 | Functional | PUBCHEM_BIOASSAY: Secondary assay for Activators of Human Pyruvate Kinase M2 isoform - Cell Titer Glo cytotoxicity assay. Measurement of cytotoxicity by measuring the total ATP content of Hela cells after 24 hrs of exposure to compound (Class of assay: confirmatory) [Related pubchem assays: 1540 (Secondary assay for Activators of Human Pyruvate Kinase M2 isoform.), 1751 (Confirmation Concentration-Response Assay for Activators of Human Muscle isoform 2 Pyruvate Kinase.), 954 (qHTS Assay for Activators of Human Muscle Pyruvate Kinase.), 1631 (qHTS Assay for Activators of Human Muscle isoform 2 Pyruvate Kinase.)] | Homo sapiens | 25 | ALA1201862 | cell-based format | PubChem BioAssays | |
| 8. | ALA1613996 | Functional | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Muscle isoform 2 Pyruvate Kinase. (Class of assay: confirmatory) [Related pubchem assays: 1379 ] | Homo sapiens | 6,326 | ALA1201862 | assay format | PubChem BioAssays | |
| 9. | ALA1614154 | Functional | PUBCHEM_BIOASSAY: Confirmation Concentration-Response Assay for Activators of Human Muscle isoform 2 Pyruvate Kinase. (Class of assay: confirmatory) [Related pubchem assays: 954, 1631 ] | Homo sapiens | 108 | ALA1201862 | assay format | PubChem BioAssays | |
| 10. | ALA1614428 | Functional | PUBCHEM_BIOASSAY: qHTS Assay for Activators of Human Muscle isoform 2 Pyruvate Kinase. (Class of assay: confirmatory) | Homo sapiens | 6,326 | ALA1201862 | assay format | PubChem BioAssays | |
| 11. | ALA1115317 | Binding | Activation of PKM2 assessed as ATP product formation by luminescent pyruvate kinase-luciferase coupled assay | 57 | ALA1156261 | single protein format | Scientific Literature | ||
| 12. | ALA1115318 | Binding | Activation of PKM2 assessed as ATP product formation at 57 uM by luminescent pyruvate kinase-luciferase coupled assay relative to fructose-1,6-bis-phosphate | 57 | ALA1156261 | single protein format | Scientific Literature | ||
| 13. | ALA1115320 | Binding | Activation of Leishmania mexicana PKM2 by quantitative high throughput screening assay | Leishmania mexicana | 57 | ALA1156261 | assay format | Scientific Literature | |
| 14. | ALA1115321 | Binding | Activation of PKM2 assessed as pyruvate formation by fluorescent pyruvate kinase-lactate dehydrogenase coupled assay | 1 | ALA1156261 | single protein format | Scientific Literature | ||
| 15. | ALA1115322 | Binding | Activation of PKM2 assessed as pyruvate formation by fluorescent pyruvate kinase-lactate dehydrogenase coupled assay relative to fructose-1,6-bis-phosphate | 1 | ALA1156261 | single protein format | Scientific Literature | ||
| 16. | ALA1115323 | Binding | Activation of PKM1 assessed as pyruvate formation by fluorescent pyruvate kinase-lactate dehydrogenase coupled assay | 57 | ALA1156261 | single protein format | Scientific Literature | ||
| 17. | ALA1115324 | Binding | Activation of PKM1 assessed as ATP product formation by luminescent pyruvate kinase-luciferase coupled assay | 57 | ALA1156261 | single protein format | Scientific Literature | ||
| 18. | ALA1108910 | Binding | Activation of PKR assessed as pyruvate formation by fluorescent pyruvate kinase-lactate dehydrogenase coupled assay relative to control | 57 | ALA1156261 | single protein format | Scientific Literature | ||
| 19. | ALA1111815 | Binding | Activation of PKR assessed as ATP product formation by luminescent pyruvate kinase-luciferase coupled assay relative to control | 57 | ALA1156261 | single protein format | Scientific Literature | ||
| 20. | ALA1111816 | Binding | Activation of PKL assessed as pyruvate formation by fluorescent pyruvate kinase-lactate dehydrogenase coupled assay relative to control | 57 | ALA1156261 | single protein format | Scientific Literature |
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