# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1114459 | Binding | Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISA | Homo sapiens | 30 | ALA1156264 | single protein format | Scientific Literature | |
2. | ALA1114464 | Binding | Ratio of RF-Pen-TGHF-valerolactam-NMeLeu-YPC IC50 to compound IC50 for soluble human FcRn | Homo sapiens | 1 | ALA1156264 | single protein format | Scientific Literature | |
3. | ALA1114472 | Functional | Increase in human IgG catabolism in iv dosed endogenous FcRn/beta2m gene knockout TG32B transgenic mouse harboring human FcRn administered QD for 4 consecutive days measured after 24 hrs by ELISA | Mus musculus | 2 | ALA1156264 | organism-based format | Scientific Literature |