| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1114459 | B | Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISA | Homo sapiens | 30 | single protein format | Scientific Literature | ||
| 2. | ALA1114467 | B | Ratio of RF-Pen-TGHFG-Sar-NMeLeu-YPC IC50 to compound IC50 for soluble human FcRn | Homo sapiens | 12 | single protein format | Scientific Literature | ||
| 3. | ALA1114469 | F | Increase in human IgG catabolism in endogenous FcRn/beta2m gene knockout TG32B transgenic mouse harboring human FcRn at 2.5 mg/kg, iv QD for 4 consecutive days measured after 24 hrs by ELISA | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 4. | ALA1114470 | F | Increase in human IgG catabolism in endogenous FcRn/beta2m gene knockout TG32B transgenic mouse harboring human FcRn at 5 mg/kg, iv QD for 4 consecutive days measured after 24 hrs by ELISA | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 5. | ALA1114471 | F | Increase in human IgG catabolism in endogenous FcRn/beta2m gene knockout TG32B transgenic mouse harboring human FcRn at 1 mg/kg, iv QD for 4 consecutive days measured after 24 hrs by ELISA | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 6. | ALA1114472 | F | Increase in human IgG catabolism in iv dosed endogenous FcRn/beta2m gene knockout TG32B transgenic mouse harboring human FcRn administered QD for 4 consecutive days measured after 24 hrs by ELISA | Mus musculus | 2 | organism-based format | Scientific Literature |
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