# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1111694 | B | Inhibition of human recombinant SPHK1 expressed in baculovirus-infected Sf9 cells in presence of sphingosine | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
2. | ALA1111695 | B | Inhibition of mouse recombinant SPHK2 expressed in baculovirus-infected Sf9 cells in presence of sphingosine | Mus musculus | 14 | cell-based format | Scientific Literature | ||
3. | ALA1111696 | F | Inhibition of S1P-induced cell proliferation of rat VSMC | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
4. | ALA1111697 | B | Inhibition of SPHKk1 in rat VSMC assessed as S1p-induced cell proliferation | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
5. | ALA1111698 | F | Inhibition of FBS-induced SPHKk1 mRNA level in rat VSMC after 4 hrs by RT-PCR | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
6. | ALA1111699 | F | Inhibition of FBS-induced SPHKk2 mRNA level in rat VSMC after 4 hrs by RT-PCR | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
7. | ALA1111700 | B | Inhibition of [32P]S1P/FBS-stimulated SPHK1 in rat VSMC after 12 hrs relative to control | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
8. | ALA1111701 | B | Inhibition of [32P]S1P/FBS-stimulated SPHK2 in rat VSMC after 12 hrs relative to control | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
9. | ALA1111702 | F | Inhibition of FBS-induced intracellular concentration of S1P in rat VSMC | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
10. | ALA1111703 | F | Inhibition of FBS-induced cell proliferation of rat VSMC after 24 hrs by BrdU incorporation assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
11. | ALA1111704 | A | Cytotoxicity against rat VSMC assessed as cell viability at 0.1 to 100 uM | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
12. | ALA1111705 | B | Ratio of Kinact to Km for human recombinant SPHK1 expressed in baculovirus-infected Sf9 cells | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
13. | ALA1111706 | B | Ratio of Kinact to Km for mouse recombinant SPHK2 expressed in baculovirus-infected Sf9 cells | Mus musculus | 14 | cell-based format | Scientific Literature | ||
14. | ALA1111707 | A | Cytotoxicity against rat VSMC assessed as cell viability at 0.1 to 100 uM by microscopical analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature |