# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1613907 | Functional | PUBCHEM_BIOASSAY: Secondary assay for Activators of Human Pyruvate Kinase M2 isoform. (Class of assay: confirmatory) [Related pubchem assays: 1634, 1631 ] | Homo sapiens | 145 | ALA1201862 | assay format | PubChem BioAssays | |
2. | ALA1115317 | Binding | Activation of PKM2 assessed as ATP product formation by luminescent pyruvate kinase-luciferase coupled assay | 57 | ALA1156261 | single protein format | Scientific Literature | ||
3. | ALA1115318 | Binding | Activation of PKM2 assessed as ATP product formation at 57 uM by luminescent pyruvate kinase-luciferase coupled assay relative to fructose-1,6-bis-phosphate | 57 | ALA1156261 | single protein format | Scientific Literature | ||
4. | ALA1115319 | Physicochemical | Kinetic solubility by quantitative nitrogen detection assay | 7 | ALA1156261 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA1115320 | Binding | Activation of Leishmania mexicana PKM2 by quantitative high throughput screening assay | Leishmania mexicana | 57 | ALA1156261 | assay format | Scientific Literature | |
6. | ALA1115323 | Binding | Activation of PKM1 assessed as pyruvate formation by fluorescent pyruvate kinase-lactate dehydrogenase coupled assay | 57 | ALA1156261 | single protein format | Scientific Literature | ||
7. | ALA1115324 | Binding | Activation of PKM1 assessed as ATP product formation by luminescent pyruvate kinase-luciferase coupled assay | 57 | ALA1156261 | single protein format | Scientific Literature | ||
8. | ALA1108910 | Binding | Activation of PKR assessed as pyruvate formation by fluorescent pyruvate kinase-lactate dehydrogenase coupled assay relative to control | 57 | ALA1156261 | single protein format | Scientific Literature | ||
9. | ALA1111815 | Binding | Activation of PKR assessed as ATP product formation by luminescent pyruvate kinase-luciferase coupled assay relative to control | 57 | ALA1156261 | single protein format | Scientific Literature | ||
10. | ALA1111816 | Binding | Activation of PKL assessed as pyruvate formation by fluorescent pyruvate kinase-lactate dehydrogenase coupled assay relative to control | 57 | ALA1156261 | single protein format | Scientific Literature | ||
11. | ALA1111817 | Binding | Activation of PKL assessed as ATP product formation by luminescent pyruvate kinase-luciferase coupled assay relative to control | 57 | ALA1156261 | single protein format | Scientific Literature | ||
12. | ALA1613982 | Functional | PUBCHEM_BIOASSAY: Confirmation Concentration-Response Assay for Activators of Human Muscle isoform 2 Pyruvate Kinase: for Probe SAR. (Class of assay: confirmatory) | 124 | ALA1201862 | assay format | PubChem BioAssays |