# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1111765 | B | Inhibition of HSV1 thymidine kinase assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintillation counting | Human alphaherpesvirus 1 | 13 | ALA1156937 | single protein format | Scientific Literature | |
2. | ALA1111767 | B | Inhibition of human recombinant cytosolic thymidine kinase 1 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintillation counting | Homo sapiens | 14 | ALA1156937 | single protein format | Scientific Literature | |
3. | ALA1111768 | B | Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintillation counting | Homo sapiens | 14 | ALA1156937 | single protein format | Scientific Literature | |
4. | ALA1111769 | B | Inhibition of Varicella zoster virus thymidine kinase assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintillation counting | Human alphaherpesvirus 3 | 13 | ALA1156937 | assay format | Scientific Literature | |
5. | ALA1111770 | B | Inhibition of Drosophila melanogaster multifunctional deoxynucleoside kinase assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintillation counting | Drosophila melanogaster | 13 | ALA1156937 | single protein format | Scientific Literature | |
6. | ALA1111771 | B | Selectivity ratio of IC50 for human recombinant cytosolic thymidine kinase 1 to IC50 for human recombinant mitochondrial thymidine kinase 2 | Homo sapiens | 2 | ALA1156937 | assay format | Scientific Literature | |
7. | ALA1111772 | B | Competitive inhibition of human recombinant mitochondrial thymidine kinase 2 using ATP as substrate by Lineweaver-Burke plotting | Homo sapiens | 1 | ALA1156937 | single protein format | Scientific Literature | |
8. | ALA1111773 | B | Uncompetitive inhibition of human recombinant mitochondrial thymidine kinase 2 using thymidine as substrate by Lineweaver-Burke plotting | Homo sapiens | 1 | ALA1156937 | single protein format | Scientific Literature | |
9. | ALA1111774 | B | Inhibition of Drosophila melanogaster multifunctional deoxynucleoside kinase expressed in thymidine kinase 2 deficient human OST cells assessed as decrease in BVDU-mediated cytotoxicity at 10 uM | Drosophila melanogaster | 1 | ALA1156937 | cell-based format | Scientific Literature | |
10. | ALA1111775 | B | Inhibition of Drosophila melanogaster multifunctional deoxynucleoside kinase expressed in thymidine kinase 2 deficient human OST cells assessed as decrease in BVDU-mediated cytotoxicity at 4 uM | Drosophila melanogaster | 1 | ALA1156937 | cell-based format | Scientific Literature |