# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1117037 | B | Displacement of [125I]NDP-alpha-MSH from human MC4R expressed in CHO cells | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
2. | ALA1117038 | F | Agonist activity at human MC4R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulation | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
3. | ALA1117039 | F | Agonist activity at human MC1R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulation | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
4. | ALA1117040 | F | Agonist activity at human MC4R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulation at 10 uM relative to alpha-MSH | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
5. | ALA1107118 | F | Agonist activity at human MC1R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulation at 10 uM relative to alpha-MSH | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
6. | ALA1107119 | B | Displacement of [125I]NDP-alpha-MSH from human MC1R expressed in CHO cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA1107120 | B | Displacement of [125I]NDP-alpha-MSH from human MC3R expressed in CHO cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
8. | ALA1107121 | B | Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in CHO cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
9. | ALA1107122 | F | Agonist activity at human MC3R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulation | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
10. | ALA1107123 | F | Agonist activity at human MC3R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulation at 10 uM relative to alpha-MSH | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
11. | ALA1107124 | F | Agonist activity at human MC5R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulation at 10 uM relative to alpha-MSH | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA1107125 | F | Agonist activity at rat MC3R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulation | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
13. | ALA1107126 | F | Agonist activity at rat MC4R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulation | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
14. | ALA1107127 | F | Agonist activity at mouse MC4R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulation | Mus musculus | 1 | cell-based format | Scientific Literature | ||
15. | ALA1107128 | F | Agonist activity at rat MC3R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulation at 10 uM relative to alpha-MSH | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
16. | ALA1107129 | F | Agonist activity at rat MC4R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulation at 10 uM relative to alpha-MSH | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
17. | ALA1107130 | F | Agonist activity at mouse MC4R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulation at 10 uM relative to alpha-MSH | Mus musculus | 1 | cell-based format | Scientific Literature | ||
18. | ALA1107131 | A | Bioavailability in Sprague-Dawley rat at 1 mg/kg, iv and 4 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
19. | ALA1107132 | A | Clearance in Sprague-Dawley rat at 1 mg/kg, iv and 4 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
20. | ALA1107133 | A | Volume of distribution at steady state in Sprague-Dawley rat at 1 mg/kg, iv and 4 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature |