# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1115329 | Functional | Agonist activity at rat mGlu4 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular calcium level after 1 hr by fluorescence microplate reader | Rattus norvegicus | 13 | ALA1156339 | cell-based format | Scientific Literature | |
2. | ALA1110789 | Functional | Agonist activity at rat mGlu4 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular inositol phosphate accumulation after 1 hr by scintillation counting | Rattus norvegicus | 18 | ALA1156339 | cell-based format | Scientific Literature | |
3. | ALA1110790 | Functional | Agonist activity at rat mGlu1 receptor expressed in HEK293 cells | Rattus norvegicus | 6 | ALA1156339 | cell-based format | Scientific Literature | |
4. | ALA1110791 | Functional | Agonist activity at rat mGlu5 receptor expressed in HEK293 cells | Rattus norvegicus | 6 | ALA1156339 | cell-based format | Scientific Literature | |
5. | ALA1110792 | Functional | Agonist activity at rat mGlu2 receptor expressed in HEK293 cells assessed as increase in intracellular calcium level after 1 hr by fluorescence microplate reader | Rattus norvegicus | 5 | ALA1156339 | cell-based format | Scientific Literature | |
6. | ALA1110794 | Functional | Agonist activity at rat mGlu6 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular calcium level after 1 hr by fluorescence microplate reader | Rattus norvegicus | 7 | ALA1156339 | cell-based format | Scientific Literature | |
7. | ALA1110796 | Functional | Agonist activity at rat mGlu7 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular calcium level after 1 hr by fluorescence microplate reader | Rattus norvegicus | 7 | ALA1156339 | cell-based format | Scientific Literature | |
8. | ALA1110798 | Functional | Agonist activity at rat mGlu8 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular calcium level after 1 hr by fluorescence microplate reader | Rattus norvegicus | 13 | ALA1156339 | cell-based format | Scientific Literature | |
9. | ALA1110799 | Functional | Agonist activity at rat mGlu8 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular inositol phosphate accumulation after 1 hr by scintillation counting | Rattus norvegicus | 13 | ALA1156339 | cell-based format | Scientific Literature | |
10. | ALA1110800 | Functional | Agonist activity at rat mGlu2 receptor expressed in HEK293 cells assessed as increase in intracellular calcium level at 100 uM after 1 hr by fluorescence microplate reader | Rattus norvegicus | 6 | ALA1156339 | cell-based format | Scientific Literature | |
11. | ALA1110801 | Binding | Selectivity ratio of EC50 for rat mGlu8 receptor to EC50 for rat mGlu4 receptor | Rattus norvegicus | 1 | ALA1156339 | assay format | Scientific Literature |