| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1117042 | B | Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISA | Rattus norvegicus | 12 | assay format | Scientific Literature | ||
| 2. | ALA1117043 | B | Inhibition of PI3K assessed as PIP3 level after 20 mins by HTRF assay | 12 | assay format | Scientific Literature | |||
| 3. | ALA1117044 | B | Selectivity ratio of IC50 for PI3K to IC50 for rat brain mTOR | 12 | assay format | Scientific Literature | |||
| 4. | ALA1117045 | F | Antiproliferative activity against human LNCAP cells after 3 days by MTS assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 5. | ALA1117046 | F | Antitumor activity against human U87MG cells xenografted in nude mouse assessed as reduction in tumor volume at 5 to 15 mg/kg, po QD for 5 days measured up to 10 days | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 6. | ALA1117047 | F | Antitumor activity against human U87MG cells xenografted in nude mouse assessed as reduction in tumor volume at 10 mg/kg, po QD for 5 days measured after 8 days relative to control | Homo sapiens | 1 | organism-based format | Scientific Literature |
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