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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA1106144 ADME Clearance in rhesus monkey at 2 mg/kg, po and 0.5 mg/kg, iv Macaca mulatta 1 ALA1156995 organism-based format Scientific Literature 2. ALA1106145 Binding Displacement of [125I]human CLR from human CGRP expressed in HEK293 cells coexpressing human RAMP1 Homo sapiens 21 ALA1156995 cell-based format Scientific Literature 3. ALA1106146 Functional Antagonist activity at human CLR expressed in human HEK293 cells coexpressing human RAMP1 assessed as Inhibition of CGRP-induced cAMP production Homo sapiens 15 ALA1156995 cell-based format Scientific Literature 4. ALA1106147 Functional Antagonist activity at human CLR expressed in human HEK293 cells coexpressing human RAMP1 assessed as Inhibition of CGRP-induced cAMP production in the presence of 50% human serum Homo sapiens 15 ALA1156995 cell-based format Scientific Literature 5. ALA1106148 ADME Oral bioavailability in rat at 10 mg/kg in presence of methylcellulose Rattus norvegicus 4 ALA1156995 organism-based format Scientific Literature 6. ALA1106149 ADME Oral bioavailability in rat at 10 mg/kg in presence of lmwitor:tween Rattus norvegicus 4 ALA1156995 organism-based format Scientific Literature 7. ALA1106152 ADME Half life in rat at 2 mg/kg, iv Rattus norvegicus 7 ALA1156995 organism-based format Scientific Literature 8. ALA1106154 ADME Clearance in rat at 10 mg/kg, po or 2 mg/kg, iv Rattus norvegicus 7 ALA1156995 organism-based format Scientific Literature 9. ALA1106156 ADME Oral bioavailability in dog at 1 mg/kg in presence of methylcellulose Canis lupus familiaris 1 ALA1156995 organism-based format Scientific Literature 10. ALA1106157 ADME Oral bioavailability in rhesus monkey at 2 mg/kg in presence of methylcellulose Macaca mulatta 1 ALA1156995 organism-based format Scientific Literature 11. ALA1106158 ADME Half life in rat at 2mg/kg, iv Rattus norvegicus 1 ALA1156995 organism-based format Scientific Literature 12. ALA1106159 ADME Half life in dog at 0.5 mg/kg, iv Canis lupus familiaris 1 ALA1156995 organism-based format Scientific Literature 13. ALA1106160 ADME Half life in rhesus monkey at 0.5 mg/kg, iv Macaca mulatta 1 ALA1156995 organism-based format Scientific Literature 14. ALA1106161 ADME Clearance in rat at 10 mg/kg, po and 2 mg/kg, iv Rattus norvegicus 1 ALA1156995 organism-based format Scientific Literature 15. ALA1106162 ADME Clearance in dog at 1 mg/kg, po and 0.5 mg/kg, iv Canis lupus familiaris 1 ALA1156995 organism-based format Scientific Literature 16. ALA1106163 Functional Inhibition of capsaicin-induced vasodilation in orally dosed rhesus monkey at 5.5 uM plasma level Macaca mulatta 1 ALA1156995 organism-based format Scientific Literature 17. ALA1106164 Functional Inhibition of capsaicin-induced vasodilation in orally dosed rhesus monkey Macaca mulatta 1 ALA1156995 organism-based format Scientific Literature