# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1108889 | Binding | Inhibition of human Kv1.5 channel expressed in CHO cells by whole cell patch clamp assay | Homo sapiens | 21 | ALA1156169 | cell-based format | Scientific Literature | |
2. | ALA1108890 | Binding | Inhibition of human ERG | Homo sapiens | 20 | ALA1156169 | single protein format | Scientific Literature | |
3. | ALA1108893 | Physicochemical | Aqueous solubility at pH 7.4 | 2 | ALA1156169 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA1108894 | Physicochemical | Aqueous solubility at pH 5.2 | 1 | ALA1156169 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA1108895 | ADME | Clearance in rat | Rattus norvegicus | 1 | ALA1156169 | organism-based format | Scientific Literature | |
6. | ALA1108896 | ADME | Volume of distribution in rat | Rattus norvegicus | 1 | ALA1156169 | organism-based format | Scientific Literature | |
7. | ALA1108897 | ADME | Half life in rat | Rattus norvegicus | 1 | ALA1156169 | organism-based format | Scientific Literature | |
8. | ALA1108898 | Functional | Antiarrhythmic activity in iv dosed rat assessed as increase in atrial refractory period after 20 mins by electrophysiological profile assay | Rattus norvegicus | 1 | ALA1156169 | organism-based format | Scientific Literature | |
9. | ALA1108899 | Functional | Antiarrhythmic activity in iv dosed rat assessed as increase in ventricular refractory period after 20 mins by electrophysiological profile assay | Rattus norvegicus | 1 | ALA1156169 | organism-based format | Scientific Literature | |
10. | ALA1108900 | Functional | Antiarrhythmic activity in iv dosed rat assessed as effect on atrioventricular refractory period after 20 mins by electrophysiological profile assay | Rattus norvegicus | 1 | ALA1156169 | organism-based format | Scientific Literature | |
11. | ALA1108901 | Functional | Antiarrhythmic activity in rat assessed as increase in atrial refractory period at 0.6 mg/kg/min, iv after 20 mins by electrophysiological profile assay | Rattus norvegicus | 1 | ALA1156169 | organism-based format | Scientific Literature | |
12. | ALA1108902 | Functional | Antiarrhythmic activity in rat assessed as increase in ventricular refractory period at 0.6 mg/kg/min, iv after 20 mins by electrophysiological profile assay | Rattus norvegicus | 1 | ALA1156169 | organism-based format | Scientific Literature | |
13. | ALA1108903 | ADME | Plasma concentration in rat at 0.01 mg/kg/min, iv after 20 mins | Rattus norvegicus | 1 | ALA1156169 | organism-based format | Scientific Literature | |
14. | ALA1108904 | ADME | Plasma concentration in rat at 0.03 mg/kg/min, iv after 20 mins | Rattus norvegicus | 1 | ALA1156169 | organism-based format | Scientific Literature | |
15. | ALA1108905 | ADME | Plasma concentration in rat at 0.06 mg/kg/min, iv after 20 mins | Rattus norvegicus | 1 | ALA1156169 | organism-based format | Scientific Literature | |
16. | ALA1108906 | ADME | Plasma concentration in rat at 0.2 mg/kg/min, iv after 20 mins | Rattus norvegicus | 1 | ALA1156169 | organism-based format | Scientific Literature | |
17. | ALA1108907 | ADME | Plasma concentration in rat at 0.6 mg/kg/min, iv after 20 mins | Rattus norvegicus | 1 | ALA1156169 | organism-based format | Scientific Literature | |
18. | ALA1108908 | ADME | Fraction unbound in human plasma | Homo sapiens | 1 | ALA1156169 | cell-free format | Scientific Literature | |
19. | ALA1108909 | Functional | Antiarrhythmic activity in dog heart failure model assessed as termination of pacing-induced atrial fibrillation | Canis lupus familiaris | 1 | ALA1156169 | organism-based format | Scientific Literature | |
20. | ALA1112660 | Functional | Antiarrhythmic activity in dog heart failure model assessed as prolongation of atrial refractory period | Canis lupus familiaris | 1 | ALA1156169 | organism-based format | Scientific Literature |