# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1112676 | Functional | Cytotoxicity against human HepG2 cells assessed as cell viability at 10 uM after 6 hrs by MTS assay | Homo sapiens | 2 | ALA1156170 | cell-based format | Scientific Literature | |
2. | ALA1112677 | Functional | Cytotoxicity against human HepG2 cells assessed as cell viability at 20 uM after 6 hrs by MTS assay | Homo sapiens | 2 | ALA1156170 | cell-based format | Scientific Literature | |
3. | ALA1112678 | Functional | Cytotoxicity against human HepG2 cells assessed as cell viability at 50 uM after 6 hrs by MTS assay | Homo sapiens | 4 | ALA1156170 | cell-based format | Scientific Literature | |
4. | ALA1112679 | Functional | Cytotoxicity against human HepG2 cells assessed as cell viability at 50 uM after 6 hrs by MTS assay relative to control | Homo sapiens | 3 | ALA1156170 | cell-based format | Scientific Literature | |
5. | ALA1112680 | Functional | Induction of nuclear NrF2 expression in wild type MEF assessed as luciferase activity at 10 to 20 uM after 24 hrs by Western blotting relative to control | Mus musculus | 2 | ALA1156170 | assay format | Scientific Literature | |
6. | ALA1112681 | Functional | Induction of GCLc in NrF2-deficient MEF at 20 uM after 24 hrs by Western blotting relative to control | Mus musculus | 1 | ALA1156170 | cell-based format | Scientific Literature | |
7. | ALA1112682 | Functional | Ratio of compound to sulforaphane activity for induction of nuclear NrF2 mediated GCLc in wild type MEF | Mus musculus | 1 | ALA1156170 | assay format | Scientific Literature | |
8. | ALA1112683 | Functional | Induction of nuclear NrF2-mediated GCLc expression in wild type MEF at 20 uM after 24 hrs by Western blotting relative to control | Mus musculus | 2 | ALA1156170 | assay format | Scientific Literature | |
9. | ALA1112685 | Functional | Induction of glutathione production in NrF2 deficient MEF at 10 uM after 24 hrs using Elmans reagent relative to control | Mus musculus | 1 | ALA1156170 | cell-based format | Scientific Literature | |
10. | ALA1112686 | Functional | Induction of glutathione production in NrF2 deficient MEF at 20 uM after 24 hrs using Elmans reagent relative to control | Mus musculus | 1 | ALA1156170 | cell-based format | Scientific Literature | |
11. | ALA1112687 | Functional | Induction of NrF2-mediated glutathione production in wild type MEF at 10 uM after 6 hrs using Elmans reagent relative to control | Mus musculus | 1 | ALA1156170 | assay format | Scientific Literature | |
12. | ALA1112688 | Functional | Induction of NrF2-mediated glutathione production in wild type MEF at 10 uM after 24 hrs using Elmans reagent relative to control | Mus musculus | 2 | ALA1156170 | assay format | Scientific Literature | |
13. | ALA1112689 | Functional | Induction of NrF2 in human HepG2 cells at 10 uM after 6 hrs by ARE-luciferase reporter gene assay | Homo sapiens | 2 | ALA1156170 | cell-based format | Scientific Literature | |
14. | ALA1112690 | Functional | Induction of NrF2 in human HepG2 cells at 20 uM after 6 hrs by ARE-luciferase reporter gene assay relative to control | Homo sapiens | 2 | ALA1156170 | cell-based format | Scientific Literature | |
15. | ALA1112691 | Functional | Induction of NrF2 in human HepG2 cells after 6 hrs by ARE-luciferase reporter gene assay | Homo sapiens | 1 | ALA1156170 | cell-based format | Scientific Literature | |
16. | ALA1112692 | Functional | Cytotoxicity against human HepG2 cells assessed as decrease in cell viability after 6 hrs by MTS assay | Homo sapiens | 1 | ALA1156170 | cell-based format | Scientific Literature | |
17. | ALA1112693 | ADME | Cytotoxicity against wild type MEF | Mus musculus | 1 | ALA1156170 | cell-based format | Scientific Literature | |
18. | ALA1112694 | ADME | Cytotoxicity against NrF2 deficient MEF | Mus musculus | 1 | ALA1156170 | cell-based format | Scientific Literature | |
19. | ALA1112695 | Functional | Ratio of compound to sulforaphane for induction of NrF2 in human HepG2 cells | Homo sapiens | 1 | ALA1156170 | cell-based format | Scientific Literature | |
20. | ALA1112696 | Functional | Cytotoxicity against human HepG2 cells assessed as decrease in cell viability at 10 to 20 uM after 6 hrs by MTS assay | Homo sapiens | 3 | ALA1156170 | cell-based format | Scientific Literature |