# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1110577 | Binding | Inhibition of human recombinant aurora B/INCENP complex after 120 mins by IMAP fluorescence polarization assay | Homo sapiens | 9 | ALA1156194 | protein complex format | Scientific Literature | |
2. | ALA1104788 | Binding | Inhibition of human Aurora B by rapid dilution method | Homo sapiens | 44 | ALA1157791 | single protein format | Scientific Literature | |
3. | ALA1104789 | ADME | Permeability by PAMPA | 1 | ALA1157791 | assay format | Scientific Literature | ||
4. | ALA1104790 | Binding | Inhibition of human Aurora B assessed as dissociation half life by rapid dilution method | Homo sapiens | 7 | ALA1157791 | single protein format | Scientific Literature | |
5. | ALA1104791 | Binding | Inhibition of human Aurora A | Homo sapiens | 44 | ALA1157791 | single protein format | Scientific Literature | |
6. | ALA1104792 | Binding | Selectivity ratio of IC50 for human Aurora A to IC50 for human Aurora B | Homo sapiens | 5 | ALA1157791 | assay format | Scientific Literature | |
7. | ALA1104794 | Functional | Antiproliferative activity against human A549 cells after 6 to 7 days by celltiter-glo luminescence assay in absence of 70% human serum albumin | Homo sapiens | 44 | ALA1157791 | cell-based format | Scientific Literature | |
8. | ALA1104798 | Functional | Selectivity ratio of EC50 for human A549 cells in presence of 70% human serum albumin to EC50 for human A549 cells in absence of 70% human serum albumin | Homo sapiens | 19 | ALA1157791 | cell-based format | Scientific Literature | |
9. | ALA1104805 | Binding | Inhibition of MET | 2 | ALA1157791 | single protein format | Scientific Literature | ||
10. | ALA1105641 | Binding | Selectivity for IGF1R over human Aurora A | 2 | ALA1157791 | assay format | Scientific Literature | ||
11. | ALA1105642 | Binding | Selectivity for LCK over human Aurora A | 2 | ALA1157791 | assay format | Scientific Literature | ||
12. | ALA1105643 | Binding | Selectivity for LYN over human Aurora A | 2 | ALA1157791 | assay format | Scientific Literature | ||
13. | ALA1105644 | Binding | Selectivity for MET over human Aurora A | 2 | ALA1157791 | assay format | Scientific Literature | ||
14. | ALA1105645 | Binding | Selectivity for ROCK over human Aurora A | 2 | ALA1157791 | assay format | Scientific Literature | ||
15. | ALA1105646 | Binding | Selectivity for SYK over human Aurora A | 2 | ALA1157791 | assay format | Scientific Literature | ||
16. | ALA1105647 | Binding | Selectivity for human Aurora B over human Aurora A | Homo sapiens | 2 | ALA1157791 | assay format | Scientific Literature | |
17. | ALA1108261 | Binding | Inhibition of IGF1R | 1 | ALA1157791 | single protein format | Scientific Literature | ||
18. | ALA1108262 | Binding | Inhibition of LYN | 1 | ALA1157791 | single protein format | Scientific Literature | ||
19. | ALA1108263 | Binding | Inhibition of ROCK1 | 1 | ALA1157791 | single protein format | Scientific Literature | ||
20. | ALA1108275 | Binding | Inhibition of human Aurora B assessed as residence time by rapid dilution method | Homo sapiens | 1 | ALA1157791 | single protein format | Scientific Literature |