# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1110576 | B | Inhibition of human recombinant aurora A/TPX2 complex after 120 mins by IMAP fluorescence polarization assay | Homo sapiens | 8 | protein complex format | Scientific Literature | ||
2. | ALA1110577 | B | Inhibition of human recombinant aurora B/INCENP complex after 120 mins by IMAP fluorescence polarization assay | Homo sapiens | 9 | protein complex format | Scientific Literature | ||
3. | ALA1110578 | B | Inhibition of aurora B assessed as inhibition of histone H3 phosphorylation by ELISA based cellular mechanistic assay | 8 | single protein format | Scientific Literature | |||
4. | ALA1110579 | F | Cytotoxicity against human A549 cells in presence of 10% human serum | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
5. | ALA1110580 | F | Cell cycle arrest in human A549 cells assessed as sub-2N DNA accumulation at 5 times EC50 after 48 hrs by FACS analysis relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
6. | ALA1110581 | F | Cell cycle arrest in human A549 cells assessed as 2N DNA accumulation at 5 times EC50 after 48 hrs by FACS analysis relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
7. | ALA1110582 | F | Cell cycle arrest in human A549 cells assessed as 2N to 4N DNA accumulation at 5 times EC50 after 48 hrs by FACS analysis relative to control relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
8. | ALA1110583 | F | Cell cycle arrest in human A549 cells assessed as 4N DNA accumulation at 5 times EC50 after 48 hrs by FACS analysis relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
9. | ALA1113413 | F | Cell cycle arrest in human A549 cells assessed as greater than 4N DNA accumulation at 5 times EC50 after 48 hrs by FACS analysis relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature |