| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1110576 | B | Inhibition of human recombinant aurora A/TPX2 complex after 120 mins by IMAP fluorescence polarization assay | Homo sapiens | 8 | protein complex format | Scientific Literature | ||
| 2. | ALA1110577 | B | Inhibition of human recombinant aurora B/INCENP complex after 120 mins by IMAP fluorescence polarization assay | Homo sapiens | 9 | protein complex format | Scientific Literature | ||
| 3. | ALA1110578 | B | Inhibition of aurora B assessed as inhibition of histone H3 phosphorylation by ELISA based cellular mechanistic assay | 8 | single protein format | Scientific Literature | |||
| 4. | ALA1110579 | F | Cytotoxicity against human A549 cells in presence of 10% human serum | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 5. | ALA1110580 | F | Cell cycle arrest in human A549 cells assessed as sub-2N DNA accumulation at 5 times EC50 after 48 hrs by FACS analysis relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 6. | ALA1110581 | F | Cell cycle arrest in human A549 cells assessed as 2N DNA accumulation at 5 times EC50 after 48 hrs by FACS analysis relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 7. | ALA1110582 | F | Cell cycle arrest in human A549 cells assessed as 2N to 4N DNA accumulation at 5 times EC50 after 48 hrs by FACS analysis relative to control relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 8. | ALA1110583 | F | Cell cycle arrest in human A549 cells assessed as 4N DNA accumulation at 5 times EC50 after 48 hrs by FACS analysis relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 9. | ALA1113413 | F | Cell cycle arrest in human A549 cells assessed as greater than 4N DNA accumulation at 5 times EC50 after 48 hrs by FACS analysis relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 10. | ALA1105351 | A | Dose normalized AUC in po dosed rat | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA1105352 | A | Oral bioavailability in rat | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA1105353 | A | Blood clearance in po dosed rat | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA4006648 | F | Antitrypanosomal activity against Trypanosoma brucei brucei Lister 427 at 18 hrs post dose by resazurin-based assay | Trypanosoma brucei brucei | 9 | assay format | Scientific Literature | ||
| 14. | ALA4006649 | A | Cytotoxicity against human HepG2 cells after 48 hrs by Cell Titer Glo assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 15. | ALA4006650 | F | Antitrypanosomal activity against Trypanosoma brucei brucei Lister 427 at 70 hrs post dose by resazurin-based assay | Trypanosoma brucei brucei | 9 | assay format | Scientific Literature |
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