# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1108112 | Binding | Displacement of [33P]sphingosine-1-phosphate from human S1P1 receptor expressed in HEK293T cells after 60 mins by scintillation counting | Homo sapiens | 16 | ALA1156167 | cell-based format | Scientific Literature | |
2. | ALA1108113 | Binding | Displacement of [33P]sphingosine-1-phosphate from human S1P3 receptor expressed in HEK293T cells after 60 mins by scintillation counting | Homo sapiens | 16 | ALA1156167 | cell-based format | Scientific Literature | |
3. | ALA1108114 | Binding | Displacement of [33P]sphingosine-1-phosphate from human S1P4 receptor expressed in HEK293T cells after 60 mins by scintillation counting | Homo sapiens | 7 | ALA1156167 | cell-based format | Scientific Literature | |
4. | ALA1108115 | Binding | Displacement of [33P]sphingosine-1-phosphate from human S1P5 receptor expressed in HEK293T cells after 60 mins by scintillation counting | Homo sapiens | 7 | ALA1156167 | cell-based format | Scientific Literature | |
5. | ALA1108116 | Binding | Selectivity ratio of IC50 for human S1P3 receptor to IC50 for human S1P1 receptor by [33P]sphingosine-1-phosphate displacement assay | Homo sapiens | 12 | ALA1156167 | assay format | Scientific Literature | |
6. | ALA1108118 | Functional | Antagonist activity at human S1P1 receptor expressed in HEK293T cells assessed as inhibition of sphingosine-1-phosphate-induced gamma-[35S]GTP binding after 30 mins by scintillation counting | Homo sapiens | 7 | ALA1156167 | cell-based format | Scientific Literature | |
7. | ALA1108119 | Functional | Antagonist activity at human S1P3 receptor expressed in HEK293T cells assessed as inhibition of sphingosine-1-phosphate-induced gamma-[35S]GTP binding after 30 mins by scintillation counting | Homo sapiens | 7 | ALA1156167 | cell-based format | Scientific Literature | |
8. | ALA1108120 | Functional | Selectivity ratio of EC50 for human S1P3 receptor to EC50 for human S1P1 receptor by gamma-[35S]GTP binding assay | Homo sapiens | 6 | ALA1156167 | assay format | Scientific Literature |