# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1108859 | Functional | Agonist activity at human recombinant MC4 receptor expressed in CHO cells by cAMP responsive beta lactamase reporter gene assay | Homo sapiens | 60 | ALA1156187 | cell-based format | Scientific Literature | |
2. | ALA1116901 | Functional | Agonist activity at human recombinant MC4 receptor expressed in CHO cells by cAMP responsive beta lactamase reporter gene assay relative to melanocortin 2 | Homo sapiens | 58 | ALA1156187 | cell-based format | Scientific Literature | |
3. | ALA1116902 | Functional | Agonist activity at human recombinant MC3 receptor expressed in CHO cells assessed as cAMP accumulation by enzyme fragment complementation assay relative to melanocortin 2 | Homo sapiens | 16 | ALA1156187 | cell-based format | Scientific Literature | |
4. | ALA1116903 | Functional | Agonist activity at human recombinant MC3 receptor expressed in CHO cells assessed as cAMP accumulation by enzyme fragment complementation assay | Homo sapiens | 27 | ALA1156187 | cell-based format | Scientific Literature | |
5. | ALA1116904 | Functional | Agonist activity at human recombinant MC1 receptor expressed in HEK293 cells assessed as cAMP accumulation by enzyme fragment complementation assay | Homo sapiens | 27 | ALA1156187 | cell-based format | Scientific Literature | |
6. | ALA1116905 | Functional | Agonist activity at human recombinant MC1 receptor expressed in HEK293 cells assessed as cAMP accumulation by enzyme fragment complementation assay relative to alpha melanocyte-stimulating hormone | Homo sapiens | 12 | ALA1156187 | cell-based format | Scientific Literature | |
7. | ALA1116906 | Functional | Agonist activity at human recombinant MC5 receptor expressed in HEK293 cells assessed as cAMP accumulation by beta lactamase reporter gene assay | Homo sapiens | 27 | ALA1156187 | cell-based format | Scientific Literature | |
8. | ALA1116907 | Functional | Agonist activity at human recombinant MC5 receptor expressed in HEK293 cells assessed as cAMP accumulation by beta lactamase reporter gene assay relative to alpha melanocyte-stimulating hormone | Homo sapiens | 13 | ALA1156187 | cell-based format | Scientific Literature | |
9. | ALA1116908 | Binding | Displacement of [3H]dofetilide from human ERG expressed in CHO cells by patch clamp method | Homo sapiens | 27 | ALA1156187 | cell-based format | Scientific Literature | |
10. | ALA1116909 | Binding | Displacement of [3H] melanocortin-2 from human recombinant MC4 receptor expressed in CHO cells by scintillation counting | Homo sapiens | 27 | ALA1156187 | cell-based format | Scientific Literature | |
11. | ALA1116910 | Physicochemical | Lipophilicity, log D at pH 7.4 | 21 | ALA1156187 | small-molecule physicochemical format | Scientific Literature | ||
12. | ALA1116911 | ADME | Intrinsic clearance in human liver microsome measured per mg of protein | Homo sapiens | 21 | ALA1156187 | microsome format | Scientific Literature |