# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1107089 | Binding | Inhibition of 17beta-HSD3 in Sprague-Dawley rat laydig cells at 100 uM | Rattus norvegicus | 22 | ALA1156212 | assay format | Scientific Literature | |
2. | ALA1108825 | Binding | Inhibition of 17beta-HSD3 in Sprague-Dawley rat testis microsomes at 100 uM | Rattus norvegicus | 23 | ALA1156212 | microsome format | Scientific Literature | |
3. | ALA1108827 | Binding | Inhibition of 17beta-HSD3 in human testis microsomes at 100 uM | Homo sapiens | 23 | ALA1156212 | microsome format | Scientific Literature | |
4. | ALA2320666 | Functional | Cytotoxicity against human HeLa cells after 48 hrs by MTT assay | Homo sapiens | 12 | ALA2311414 | cell-based format | Scientific Literature | |
5. | ALA2320667 | Functional | Cytotoxicity against human MOLT4 cells after 48 hrs by MTT assay | Homo sapiens | 12 | ALA2311414 | cell-based format | Scientific Literature | |
6. | ALA2320668 | Functional | Cytotoxicity against human KB cells after 48 hrs by MTT assay | Homo sapiens | 12 | ALA2311414 | cell-based format | Scientific Literature | |
7. | ALA2320669 | Functional | Cytotoxicity against human PC3 cells after 48 hrs by MTT assay | Homo sapiens | 12 | ALA2311414 | cell-based format | Scientific Literature | |
8. | ALA2320670 | Functional | Cytotoxicity against human DU145 cells after 48 hrs by MTT assay | Homo sapiens | 12 | ALA2311414 | cell-based format | Scientific Literature | |
9. | ALA2320671 | Functional | Antimalarial activity against chloroquine-sensitive Plasmodium falciparum D6 infected in RBC assessed as plasmodial LDH activity after 72 hrs | Plasmodium falciparum | 22 | ALA2311414 | organism-based format | Scientific Literature | |
10. | ALA2320672 | Functional | Antimalarial activity against chloroquine-resistant Plasmodium falciparum W2 infected in RBC assessed as plasmodial LDH activity after 72 hrs | Plasmodium falciparum | 22 | ALA2311414 | organism-based format | Scientific Literature | |
11. | ALA2320673 | Toxicity | Selectivity index, ratio of IC50 for african green monkey Vero cells to IC50 for chloroquine-sensitive Plasmodium falciparum D6 | 18 | ALA2311414 | cell-based format | Scientific Literature | ||
12. | ALA2320674 | Toxicity | Selectivity index, ratio of IC50 for african green monkey Vero cells to IC50 for chloroquine-resistant Plasmodium falciparum W2 | 18 | ALA2311414 | cell-based format | Scientific Literature | ||
13. | ALA2320675 | ADME | Cytotoxicity against african green monkey Vero cells up to 9 uM after 48 hrs by neutral red assay | Chlorocebus sabaeus | 22 | ALA2311414 | cell-based format | Scientific Literature |