# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1108824 | Binding | Inhibition of 17beta-HSD3 in Sprague-Dawley rat laydig cells | Rattus norvegicus | 5 | ALA1156212 | assay format | Scientific Literature | |
2. | ALA1108825 | Binding | Inhibition of 17beta-HSD3 in Sprague-Dawley rat testis microsomes at 100 uM | Rattus norvegicus | 23 | ALA1156212 | microsome format | Scientific Literature | |
3. | ALA1108827 | Binding | Inhibition of 17beta-HSD3 in human testis microsomes at 100 uM | Homo sapiens | 23 | ALA1156212 | microsome format | Scientific Literature | |
4. | ALA2405592 | Binding | Inhibition of 11beta-HSD2 in human kidney microsomes using [3H]-cortisol as substrate assessed as formation of cortisone at 100 uM after 30 mins by radiometric analysis relative to control | Homo sapiens | 36 | ALA2401685 | microsome format | Scientific Literature | |
5. | ALA2405593 | Binding | Inhibition of 11beta-HSD2 in rat kidney microsomes using [3H]-CORT as substrate assessed as formation of 11-DHC at 100 uM after 30 mins by radiometric analysis relative to control | Rattus norvegicus | 36 | ALA2401685 | microsome format | Scientific Literature | |
6. | ALA2405597 | Binding | Inhibition of human 11beta-HSD1 transfected in CHOP cells at 100 uM relative to control | Homo sapiens | 25 | ALA2401685 | cell-based format | Scientific Literature | |
7. | ALA2405598 | Binding | Inhibition of 11beta-HSD1 in Sprague-Dawley rat leydig cells at 100 uM | Rattus norvegicus | 15 | ALA2401685 | assay format | Scientific Literature | |
8. | ALA2405604 | Binding | Inhibition of 11beta-HSD1 in rat testis microsomes using [3H]-11-DHC as substrate assessed as formation of CORT at 100 uM after 60 to 90 mins by radiometric analysis relative to control | Rattus norvegicus | 27 | ALA2401685 | microsome format | Scientific Literature | |
9. | ALA2405606 | Binding | Inhibition of 11beta-HSD1 in human liver microsomes using [3H]-cortisone as substrate assessed as formation of cortisol at 100 uM after 60 to 90 mins by radiometric analysis relative to control | Homo sapiens | 26 | ALA2401685 | microsome format | Scientific Literature |