# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1111634 | P | Association constant pKa of the compound | 10 | small-molecule physicochemical format | Scientific Literature | |||
2. | ALA1111635 | F | Agonist activity at turkey P2Y1 receptor expressed in human 132N1 receptor assessed as induction of intracellular calcium mobilization | Meleagris gallopavo | 8 | cell-based format | Scientific Literature | ||
3. | ALA1111637 | P | Chemical stability assessed as enzymatic stability at 100 uM after 20 mins in presence of human NTPDase1 | 7 | small-molecule physicochemical format | Scientific Literature | |||
4. | ALA1111638 | P | Chemical stability assessed as enzymatic stability at 100 uM after 20 mins in presence of human NTPDase2 | 7 | small-molecule physicochemical format | Scientific Literature | |||
5. | ALA1111639 | P | Chemical stability assessed as enzymatic stability at 100 uM after 20 mins in presence of human NTPDase3 | 7 | small-molecule physicochemical format | Scientific Literature | |||
6. | ALA1111640 | P | Chemical stability assessed as enzymatic stability at 100 uM after 20 mins in presence of human NTPDase8 | 7 | small-molecule physicochemical format | Scientific Literature | |||
7. | ALA1111641 | P | Chemical stability assessed as enzymatic stability at 100 uM after 20 mins in presence of human NPP1 | 7 | small-molecule physicochemical format | Scientific Literature | |||
8. | ALA1111642 | P | Chemical stability assessed as enzymatic stability at 100 uM after 20 mins in presence of human NPP3 | 7 | small-molecule physicochemical format | Scientific Literature | |||
9. | ALA1111643 | F | Antihypertensive activity in New Zealand rabbit assessed as reduction in intraocular pressure at 100 uM after 8 hrs relative to control | Oryctolagus cuniculus | 7 | organism-based format | Scientific Literature | ||
10. | ALA1111644 | F | Antihypertensive activity in New Zealand rabbit assessed as reduction in intraocular pressure at 1 nM to 100 uM after 8 hrs relative to control | Oryctolagus cuniculus | 4 | organism-based format | Scientific Literature | ||
11. | ALA3089316 | B | Competitive inhibition of human NPP1 expressed in COS7 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate preincubated at 25 to 100 uM for 3 mins before substrate addition measured after 15 mins by Dixon/Cornish Bowden method | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
12. | ALA3089666 | B | Inhibition of NPP3 in human HTB-85 cells assessed as production of p-nitrophenol using pnp-TMP at 100 uM measured after 20 mins by spectrophotometry | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
13. | ALA3089667 | B | Inhibition of NPP1 in human HTB-85 cells assessed as production of p-nitrophenol using pnp-TMP at 100 uM measured after 20 mins by spectrophotometry | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
14. | ALA3089668 | B | Inhibition of human NTPDase8 assessed as amount of inorganic phosphate released using ATP as the substrate preincubated at 100 uM for 3 mins before substrate addition after 15 mins by malachite green reagent method | Homo sapiens | 9 | single protein format | Scientific Literature | ||
15. | ALA3089669 | B | Inhibition of human NTPDase3 assessed as amount of inorganic phosphate released using ATP as the substrate preincubated at 100 uM for 3 mins before substrate addition after 15 mins by malachite green reagent method | Homo sapiens | 9 | single protein format | Scientific Literature | ||
16. | ALA3089670 | B | Inhibition of human NTPDase2 assessed as amount of inorganic phosphate released using ATP as the substrate preincubated at 100 uM for 3 mins before substrate addition after 15 mins by malachite green reagent method | Homo sapiens | 7 | single protein format | Scientific Literature | ||
17. | ALA3089671 | B | Inhibition of human NTPDase1 assessed as amount of inorganic phosphate released using ATP as the substrate preincubated at 100 uM for 3 mins before substrate addition after 15 mins by malachite green reagent method | Homo sapiens | 9 | single protein format | Scientific Literature | ||
18. | ALA3089711 | B | Inhibition of human NPP3 expressed in COS7 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate preincubated at 100 uM for 3 mins before substrate addition measured after 15 mins by HPLC analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
19. | ALA3089712 | B | Inhibition of human NPP1 expressed in COS7 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate preincubated at 100 uM for 3 mins before substrate addition measured after 15 mins by HPLC analysis | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
20. | ALA3089713 | B | Mixed type inhibition of human NPP1 expressed in COS7 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate preincubated for 3 mins before substrate addition measured after 15 mins by Dixon/Cornish Bowden method | Homo sapiens | 7 | cell-based format | Scientific Literature |