| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1115235 | B | Inhibition of human recombinant C-terminal FLAG-tagged autotaxin expressed in baculovirus-infected Sf9 cells assessed as FS-3 hydrolysis at 10 uM relative to control | Homo sapiens | 103 | cell-based format | Scientific Literature | ||
| 2. | ALA1273379 | B | Inhibition of His6x-tagged PRMT1-mediated protein arginine methylation expressed in Escherichia coli BL21 (DE3) using H4(1-20) and [14C]-SAM by scintillation counting | 12 | assay format | Scientific Literature | |||
| 3. | ALA1273380 | B | Inhibition of His6x-tagged PRMT1-mediated protein arginine methylation expressed in Escherichia coli BL21 (DE3) using GAR R4 peptide and [14C]-AdoMet by scintillation counting | 9 | assay format | Scientific Literature | |||
| 4. | ALA1273383 | B | Binding affinity to His6x-tagged PRMT1 expressed in Escherichia coli BL21 (DE3) using fluorescein-labeled H4(1-20) peptide substrate by spectrofluorimeter analysis | 1 | assay format | Scientific Literature | |||
| 5. | ALA1273384 | B | Inhibition of human GST-tagged PRMT1-mediated arginine methylation expressed in Escherichia coli BL21 (DE3) using H4(1-20) and [14C]-AdoMet by scintillation counting | Homo sapiens | 10 | assay format | Scientific Literature | ||
| 6. | ALA1273387 | B | Competitive inhibition of rat His6x-tagged PRMT1 expressed in Escherichia coli BL21 (DE3) using H4(1-20) substrate by double-reciprocal plotting | Rattus norvegicus | 2 | assay format | Scientific Literature | ||
| 7. | ALA1273388 | B | Non-competitive inhibition of rat His6x-tagged PRMT1 expressed in Escherichia coli BL21 (DE3) using [14C]-AdoMet substrate by double-reciprocal plotting | Rattus norvegicus | 2 | assay format | Scientific Literature | ||
| 8. | ALA1273390 | B | Inhibition of His6x-tagged PRMT3-mediated arginine methylation expressed in Escherichia coli BL21 (DE3) using GAR R4 peptide and [14C]-SAM by scintillation counting | 1 | assay format | Scientific Literature | |||
| 9. | ALA1273735 | B | Inhibition of mouse GST-tagged CARM1-mediated arginine methylation expressed in Escherichia coli BL21 (DE3) using H3(1-31) and [14C]-SAM by scintillation counting | Mus musculus | 1 | assay format | Scientific Literature | ||
| 10. | ALA1273736 | B | Inhibition of His6x-tagged PRMT6-mediated arginine methylation expressed in Escherichia coli BL21 (DE3) using H3(1-31) peptide and [14C]-SAM by scintillation counting | 1 | assay format | Scientific Literature | |||
| 11. | ALA1273737 | B | Selectivity ratio of IC50 for His6x-tagged PRMT1 to IC50 for His6x-tagged PRMT6 | 1 | assay format | Scientific Literature | |||
| 12. | ALA1273738 | B | Binding affinity to PRMT1 expressed in Escherichia coli BL21 (DE3) at 200 uM by MALDI-MS analysis | 2 | assay format | Scientific Literature | |||
| 13. | ALA1273739 | B | Binding affinity to His6x-tagged PRMT1 expressed in Escherichia coli BL21 (DE3) assessed as reduction of absorbance at 40 uM by UV-vis spectra analysis | 1 | assay format | Scientific Literature | |||
| 14. | ALA1273740 | B | Inhibition of His6x-tagged PRMT1-mediated arginine methylation expressed in Escherichia coli BL21 (DE3) using H4(1-11) and [14C]-SAM by scintillation counting | 2 | assay format | Scientific Literature | |||
| 15. | ALA1273742 | B | Inhibition of HAT p300-mediated arginine methylation using H4(1-20) and [14C]-acetyl CoA by scintillation counting | 2 | single protein format | Scientific Literature | |||
| 16. | ALA2175631 | B | Inhibition of histidine tagged recombinant PRMT1 expressed in Escherichia coli BL21 (DE3) cells using Histone H4(1-20) substrate preincubated for 5 mins measured after 8 mins by liquid scintillation counting | 4 | cell-based format | Scientific Literature |
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