# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1115415 | B | Inhibition of human PARP1 by SPA | Homo sapiens | 30 | ALA1157008 | single protein format | Scientific Literature | |
2. | ALA1115416 | B | Inhibition of PARP in hydrogen peroxide-induced human HeLa cells assessed as inhibition DNA-damage-induced PARylation | Homo sapiens | 30 | ALA1157008 | cell-based format | Scientific Literature | |
3. | ALA1115417 | F | Antiproliferative activity against BRCA1 deficient human HeLa cells after 7 days by cell titer-blue assay | Homo sapiens | 22 | ALA1157008 | cell-based format | Scientific Literature | |
4. | ALA1115418 | F | Antiproliferative activity against human HeLa cells expressing wild type BRCA1 after 7 days by cell titer-blue assay | Homo sapiens | 22 | ALA1157008 | cell-based format | Scientific Literature | |
5. | ALA1115419 | A | Intrinsic clearance in rat liver microsomes assessed per mg of protein up to 90 mins | Rattus norvegicus | 16 | ALA1157008 | microsome format | Scientific Literature | |
6. | ALA1115420 | A | Intrinsic clearance in mouse liver microsomes assessed per mg of protein up to 90 mins | Mus musculus | 16 | ALA1157008 | microsome format | Scientific Literature | |
7. | ALA1115421 | A | Plasma clearance in rat | Rattus norvegicus | 16 | ALA1157008 | organism-based format | Scientific Literature | |
8. | ALA1116315 | A | Intrinsic clearance in rat liver microsomes assessed per mg of protein up to 60 mins in presence of rat recombinant CYP1A2 | Rattus norvegicus | 16 | ALA1157008 | microsome format | Scientific Literature | |
9. | ALA3428885 | B | Inhibition of PARP1 (unknown origin) | Homo sapiens | 17 | ALA3425485 | single protein format | Scientific Literature | |
10. | ALA3428886 | B | Inhibition of PARP in human HeLa cells assessed as inhibition of hydrogen peroxide-induced PARylation by cell-based assay | Homo sapiens | 9 | ALA3425485 | cell-based format | Scientific Literature | |
11. | ALA3429570 | A | Intrinsic clearance in rat liver microsomes measured per mg of protein | Rattus norvegicus | 8 | ALA3425485 | assay format | Scientific Literature | |
12. | ALA3429578 | A | Drug metabolism assessed as recombinant CYP1A1 (unknown origin)-mediated compound intrinsic clearance measured per mg of protein | Homo sapiens | 8 | ALA3425485 | single protein format | Scientific Literature |