# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1109952 | Binding | Inhibition of AKT | 21 | ALA1157000 | single protein format | Scientific Literature | ||
2. | ALA1109953 | Binding | Inhibition of AKT2 | 21 | ALA1157000 | single protein format | Scientific Literature | ||
3. | ALA1109954 | Binding | Inhibition of AKT3 | 21 | ALA1157000 | single protein format | Scientific Literature | ||
4. | ALA1109955 | Binding | Inhibition of GSK3-beta phosphorylation in human BT474 cells | Homo sapiens | 21 | ALA1157000 | cell-based format | Scientific Literature | |
5. | ALA1109956 | Functional | Antiproliferative activity against human BT474 cells | Homo sapiens | 21 | ALA1157000 | cell-based format | Scientific Literature | |
6. | ALA1109957 | Functional | Antiproliferative activity against human LNCAP cells | Homo sapiens | 21 | ALA1157000 | cell-based format | Scientific Literature | |
7. | ALA1109958 | Functional | Antiproliferative activity against human HFF cells | Homo sapiens | 21 | ALA1157000 | cell-based format | Scientific Literature | |
8. | ALA3988182 | Functional | GSK PKIS2: Screen against O. lienalis microfilariae, single point, at 3.1uM to assess reduction in motility. Compounds were also tested for cytotoxicity against Rhesus Monkey LLCMK2 cells. A score was assigned as follows: Score 3 = Good activity, 100 % motility reduction; Score 2 = Marginal/moderate activity, 50-99% motility reduction; Score 1 = Inactive, <50% motility reduction; Score 0 = Cytotoxic. | Onchocerca lienalis | 486 | ALA3988181 | cell-based format | Published Kinase Inhibitor Set 2 |