| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1831696 | F | Cytotoxicity against mouse J774 cells assessed as reduction in cell viability after 48 hrs | Mus musculus | 5 | cell-based format | Scientific Literature | ||
| 2. | ALA1831697 | B | Inhibition of RGGT assessed as [3H]GGPP incorporation into Rab1a protein after 30 mins | 5 | assay format | Scientific Literature | |||
| 3. | ALA1831698 | B | Inhibition of RGGT in cell-based assay assessed as inhibition of Rab11 prenylation after 24 hrs by Western blot analysis | 5 | cell-based format | Scientific Literature | |||
| 4. | ALA1109110 | B | Inhibition of human FPPS after 10 mins using [14C]IPP as substrate by liquid scintillation counting | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 5. | ALA1109111 | F | Cytotoxicity against mouse J774 cells assessed as cell viability after 48 hrs by alamar blue assay | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 6. | ALA1109112 | B | Inhibition of recombinant RGGT assessed as incorporation of [3H]GGPP into His-tagged canine rab1a after 30 mins | 3 | assay format | Scientific Literature | |||
| 7. | ALA1110028 | B | Inhibition of recombinant RGGT assessed as incorporation of [3H]GGPP into His-tagged canine rab1a after 20 mins | 2 | assay format | Scientific Literature | |||
| 8. | ALA1110029 | B | Inhibition of RGGT-mediated Rab11 prenylation in mouse J774 cells after 24 hrs by Western blot analysis | Mus musculus | 4 | cell-based format | Scientific Literature | ||
| 9. | ALA1110030 | B | Inhibition of RGGT-mediated Rap1A prenylation in mouse J774 cells after 24 hrs by Western blot analysis | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA1110033 | B | Inhibition of GGPPS after 10 mins using [14C]IPP as substrate by liquid scintillation counting | 4 | single protein format | Scientific Literature | |||
| 11. | ALA1110034 | B | Inhibition of GGTase1 assessed as incorporation of [3H]GGPP into His-tagged canine rab1a after 30 mins | 4 | assay format | Scientific Literature | |||
| 12. | ALA1110035 | B | Inhibition of recombinant RGGT by uncompetitive inhibition based Lineweaver-Burke plot using Rab1a as substrate | 2 | assay format | Scientific Literature | |||
| 13. | ALA1110036 | B | Inhibition of GGPPS at 1mM after 10 mins using [14C]IPP as substrate by liquid scintillation counting | 1 | single protein format | Scientific Literature | |||
| 14. | ALA1110037 | B | Inhibition of GGTase1 assessed as incorporation of [3H]GGPP into His-tagged canine rab1a at 1 mM after 30 mins | 1 | single protein format | Scientific Literature | |||
| 15. | ALA1110038 | B | Inhibition of rabbit osteoclast rab11 prenylation after 24 hrs by Western blot analysis | Oryctolagus cuniculus | 2 | single protein format | Scientific Literature | ||
| 16. | ALA1110039 | F | Antiresorptive activity in rabbit osteoclasts assessed as number of actin rings after 48 hrs using TRITC-phelloidin stain relative to control | Oryctolagus cuniculus | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA1110040 | F | Antiresorptive activity in Schenk growing rat model assessed as inhibition of bone resorption | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 18. | ALA1110041 | B | Inhibition of human FPPS at 10 uM after 10 mins using [14C]IPP as substrate | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 19. | ALA3224126 | B | Inhibition of rat RabGGTase using [3H]GGPP by scintillation counting | Rattus norvegicus | 5 | assay format | Scientific Literature | ||
| 20. | ALA4020300 | F | Cytotoxicity against human HeLa cells assessed as reduction of cell viability in FBS-supplemented medium after 72 hrs by prestoblue assay | Homo sapiens | 10 | cell-based format | Scientific Literature |
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