# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1109141 | Binding | Inhibition of GST-tagged PLK1 expressed in H5 insect cells assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting | 47 | ALA1157785 | cell-based format | Scientific Literature | ||
2. | ALA1109142 | Binding | Inhibition of Plk2 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting | 25 | ALA1157785 | single protein format | Scientific Literature | ||
3. | ALA1109143 | Binding | Inhibition of Plk3 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting | 25 | ALA1157785 | single protein format | Scientific Literature | ||
4. | ALA1109144 | Physicochemical | Solubility at pH 7 after 24 hrs by LC-MS/MS analysis | 25 | ALA1157785 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA1109145 | Binding | Inhibition of CDK2/Cyclin A assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting | 47 | ALA1157785 | protein complex format | Scientific Literature | ||
6. | ALA1109146 | Binding | Inhibition of Aurora A assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting | 47 | ALA1157785 | single protein format | Scientific Literature | ||
7. | ALA1109150 | Functional | Antiproliferative activity against human A2780 cells assessed as intracellular ATP level after 72 hrs by luminometry | Homo sapiens | 47 | ALA1157785 | cell-based format | Scientific Literature | |
8. | ALA1109151 | Binding | Inhibition of CK2 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting | 1 | ALA1157785 | assay format | Scientific Literature | ||
9. | ALA1109152 | Binding | Inhibition of CDK1/Cyclin B assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting | 1 | ALA1157785 | protein complex format | Scientific Literature | ||
10. | ALA1109153 | Binding | Inhibition of CDK5/p25 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting | 1 | ALA1157785 | protein complex format | Scientific Literature | ||
11. | ALA1109154 | Binding | Inhibition of CDK2/Cyclin E assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting | 1 | ALA1157785 | protein complex format | Scientific Literature | ||
12. | ALA1109155 | Binding | Inhibition of VEGFR3 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting | 1 | ALA1157785 | single protein format | Scientific Literature | ||
13. | ALA1109156 | Binding | Inhibition of PDGFR assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting | 1 | ALA1157785 | assay format | Scientific Literature | ||
14. | ALA1109157 | Binding | Inhibition of KIT assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting | 1 | ALA1157785 | single protein format | Scientific Literature | ||
15. | ALA1109158 | Binding | Inhibition of c-ABL assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting | 1 | ALA1157785 | single protein format | Scientific Literature | ||
16. | ALA1109159 | Binding | Inhibition of AKT1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting | 1 | ALA1157785 | single protein format | Scientific Literature | ||
17. | ALA1109160 | Binding | Inhibition of ALK assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting | 1 | ALA1157785 | single protein format | Scientific Literature | ||
18. | ALA1109161 | Binding | Inhibition of Aurora B assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting | 1 | ALA1157785 | single protein format | Scientific Literature | ||
19. | ALA1109162 | Binding | Inhibition of CDC7 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting | 1 | ALA1157785 | single protein format | Scientific Literature | ||
20. | ALA1109163 | Binding | Inhibition of CDK7 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting | 1 | ALA1157785 | single protein format | Scientific Literature |