# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1121265 | Functional | Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calcium flux by FLIPR assay | Homo sapiens | 63 | ALA1157756 | cell-based format | Scientific Literature | |
2. | ALA1121266 | ADME | Clearance in dog | Canis lupus familiaris | 2 | ALA1157756 | organism-based format | Scientific Literature | |
3. | ALA1121267 | ADME | Half life in dog | Canis lupus familiaris | 2 | ALA1157756 | organism-based format | Scientific Literature | |
4. | ALA1121268 | ADME | Volume of distribution at steady state in dog | Canis lupus familiaris | 1 | ALA1157756 | organism-based format | Scientific Literature | |
5. | ALA1121282 | Functional | Agonist activity at human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calcium flux by FLIPR assay relative to glutamate | Homo sapiens | 2 | ALA1157756 | cell-based format | Scientific Literature | |
6. | ALA1121283 | Functional | Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calcium flux by FLIPR assay relative to glutamate | Homo sapiens | 2 | ALA1157756 | cell-based format | Scientific Literature | |
7. | ALA1121284 | Functional | Agonist activity at human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calcium flux by LIPR assay | Homo sapiens | 2 | ALA1157756 | cell-based format | Scientific Literature | |
8. | ALA1121286 | Binding | Efflux ratio of human P-glycoprotein-mediated permeability from apical to basolateral over basolateral to apical side | Homo sapiens | 2 | ALA1157756 | assay format | Scientific Literature | |
9. | ALA1121287 | Binding | Apparent permeability of human P-glycoprotein-mediated drug efflux | Homo sapiens | 2 | ALA1157756 | assay format | Scientific Literature | |
10. | ALA1121288 | Binding | Efflux ratio of rat P-glycoprotein-mediated permeability from apical to basolateral over basolateral to apical side | Rattus norvegicus | 2 | ALA1157756 | assay format | Scientific Literature | |
11. | ALA1121289 | Binding | Apparent permeability of rat P-glycoprotein-mediated drug efflux | Rattus norvegicus | 2 | ALA1157756 | assay format | Scientific Literature |