# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1120985 | Functional | Antagonist activity at Gal4-fused mineralocorticoid receptor expressed in human HuH7 cells assessed as inhibition of aldosterone-induced receptor activation by luciferase reporter gene assay | 16 | ALA1157753 | cell-based format | Scientific Literature | ||
2. | ALA1120986 | Binding | Inhibition of L-type calcium channel in rat A10 cells assessed as inhibition of depolarization-induced increase in calcium flux after 48 hrs by FLIPR assay | Rattus norvegicus | 16 | ALA1157753 | cell-based format | Scientific Literature | |
3. | ALA1121072 | Functional | Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current at 200 nM by FLIPR calcium 4 assay | Rattus norvegicus | 27 | ALA1158565 | cell-based format | Scientific Literature | |
4. | ALA1121077 | Functional | Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current at 200 nM by FLIPR calcium 4 assay | Oryctolagus cuniculus | 27 | ALA1158565 | cell-based format | Scientific Literature | |
5. | ALA1121082 | Functional | Selectivity ratio of antagonist activity at rat Cav1.3 to antagonist activity at rabbit Cav1.2 at 200 nM | 27 | ALA1158565 | assay format | Scientific Literature | ||
6. | ALA1219573 | Functional | Antagonist activity at mineralocorticoid receptor LBD expressed in human HUH7 cells coexpressing GAL4 by luciferase reporter gene assay | 47 | ALA1212896 | cell-based format | Scientific Literature |