# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1121290 | Functional | Cytotoxicity against human RPMI8402 cells after 4 days by MTT assay | Homo sapiens | 26 | ALA1157757 | cell-based format | Scientific Literature | |
2. | ALA1121291 | Functional | Cytotoxicity against wild type human KB3-1 cells after 4 days by MTT assay | Homo sapiens | 26 | ALA1157757 | cell-based format | Scientific Literature | |
3. | ALA1121292 | Functional | Cytotoxicity against multidrug-resistant human KBV1 cells expressing MDR1 after 4 days by MTT assay | Homo sapiens | 26 | ALA1157757 | cell-based format | Scientific Literature | |
4. | ALA1121293 | Functional | Cytotoxicity against multidrug-resistant human KBH5.0 cells expressing BCRP after 4 days by MTT assay | Homo sapiens | 26 | ALA1157757 | cell-based format | Scientific Literature | |
5. | ALA1121294 | Functional | Antitumor activity against human MDA-MB-435 cells xenografted in NcR nu/nu mouse assessed as reduction of tumor volume at 20 mg/kg, ip administered 3 times weekly on alternate days for 31 days | Homo sapiens | 1 | ALA1157757 | organism-based format | Scientific Literature | |
6. | ALA1121295 | Functional | Antitumor activity against human MDA-MB-435 cells xenografted in NcR nu/nu mouse assessed as reduction of tumor volume at 28.8 mg/kg, ip administered 3 times weekly on alternate days for 31 days | Homo sapiens | 1 | ALA1157757 | organism-based format | Scientific Literature | |
7. | ALA1121296 | Binding | Binding affinity to human G-quadruplex d[T2G3(T2AG3)3A] DNA assessed as change in transition temperature at 20 uM in presence of 150 mM K+ ions | Homo sapiens | 4 | ALA1157757 | nucleic acid format | Scientific Literature | |
8. | ALA1121297 | Binding | Binding affinity to r[AG4CG2-CUG2UCG2AGUG2C] sequence of quadruplex RNA assessed as change in transition temperature at 20 uM in presence of 150 mM K+ ions | 4 | ALA1157757 | nucleic acid format | Scientific Literature | ||
9. | ALA1121298 | Binding | Binding affinity to Salmon testes duplex DNA assessed as change in transition temperature at 15 uM in presence of 150 mM K+ ions | Salmonidae | 3 | ALA1157757 | nucleic acid format | Scientific Literature | |
10. | ALA1121299 | Binding | Binding affinity to Salmon testes poly(rA).poly(rU) duplex RNA assessed as change in transition temperature at 15 uM in presence of 150 mM K+ ions | Salmonidae | 3 | ALA1157757 | nucleic acid format | Scientific Literature |