| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1121301 | F | Antiproliferative activity against human HeLa cells by [3H]thymidine incorporation | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 2. | ALA1226411 | F | Inhibition of protein synthesis in human HeLa cells after 50 mins by [35S]methionine metabolic labeling study | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA1226412 | F | Inhibition of protein synthesis in human HeLa cells at 1 uM by [35S]methionine metabolic labeling study | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA1226413 | F | Inhibition of DNA synthesis in human HeLa cells assessed as [3H] thymidine incorporation at 1 uM by scintillation counting | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA1226414 | F | Inhibition of RNA synthesis in human HeLa cells assessed as [3H] Uridine incorporation at 1 uM by scintillation counting | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA1226415 | F | Inhibition of protein synthesis in human HeLa cells at 1 uM after 60 mins by [35S]methionine metabolic labeling study | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA1226416 | F | Inhibition of 80S ribosome complex formation in rabbit reticulocyte lysate in presence of 600 uM cyclohexamide assessed as increase in unbound mRNA at 50 uM | Oryctolagus cuniculus | 1 | assay format | Scientific Literature | ||
| 8. | ALA1226417 | F | Inhibition of 48S ribosome complex formation in wheat germ extract in presence of 1 mM GMP-PNP assessed as increase in unbound mRNA at 50 uM | Triticum aestivum | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA1226418 | B | Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabolic labeling study | Mus musculus | 19 | assay format | Scientific Literature | ||
| 10. | ALA1226419 | B | Inhibition of HCV IRES-mediated protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract at 50 uM by [35S]methionine metabolic labeling study | Hepacivirus hominis | 1 | assay format | Scientific Literature | ||
| 11. | ALA1226420 | B | Inhibition of eIF4A-mediated cap-dependent protein synthesis in rabbit reticulocyte lysate transfected with FF-HCV-Ren mRNA by [35S]methionine metabolic labeling study | Oryctolagus cuniculus | 1 | assay format | Scientific Literature | ||
| 12. | ALA1226421 | B | Inhibition of eIF4A-mediated cap-dependent protein synthesis in wheat germ extract transfected with FF-HCV-Ren mRNA by [35S]methionine metabolic labeling study | Triticum aestivum | 1 | assay format | Scientific Literature | ||
| 13. | ALA1226422 | B | Inhibition of eIF4A-mediated cap-dependent protein synthesis in Escherichia coli S30 extract transfected with FF-HCV-Ren mRNA at 50 uM by [35S]methionine metabolic labeling study | Escherichia coli | 1 | assay format | Scientific Literature | ||
| 14. | ALA1226423 | B | Inhibition of eIF4A interaction with mRNA cap structure in presence of 0.6 mM m7 GDP at 50 uM by chemical cross-linking assay | 1 | single protein format | Scientific Literature | |||
| 15. | ALA1226424 | B | Inhibition of eIF4B interaction with mRNA cap structure in presence of 0.6 mM m7GDP at 50 uM by chemical cross-linking assay | 1 | single protein format | Scientific Literature | |||
| 16. | ALA1226425 | B | Inhibition of eIF4E interaction with mRNA cap structure in presence of 0.6 mM m7 GDP at 50 uM by chemical cross-linking assay | 1 | single protein format | Scientific Literature | |||
| 17. | ALA1226426 | B | Inhibition of eIF4A RNA-dependent ATPase activity assessed as rate of ATP hydrolysis | 1 | single protein format | Scientific Literature | |||
| 18. | ALA1226427 | B | Inhibition of eIF4A-mediated helicase activity by helicase assay | 1 | single protein format | Scientific Literature | |||
| 19. | ALA1226428 | B | Inhibition of DED1-mediated helicase activity by helicase assay | 1 | assay format | Scientific Literature | |||
| 20. | ALA1226429 | B | Inhibition of eIF4A-mediated cap-dependent translation in Swiss mouse Krebs2 extract transfected with bicistronic mRNA by [35S]methionine metabolic labeling study | Mus musculus | 1 | assay format | Scientific Literature |
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