# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1121070 | Functional | Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current at 1000 nM by FLIPR calcium 4 assay | Rattus norvegicus | 13 | ALA1158565 | cell-based format | Scientific Literature | |
2. | ALA1121075 | Functional | Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current at 1000 nM by FLIPR calcium 4 assay | Oryctolagus cuniculus | 13 | ALA1158565 | cell-based format | Scientific Literature | |
3. | ALA1121080 | Functional | Selectivity ratio of antagonist activity at rat Cav1.3 to antagonist activity at rabbit Cav1.2 at 1000 nM | 13 | ALA1158565 | assay format | Scientific Literature | ||
4. | ALA2067436 | Binding | Potentiation of forskolin-induced CFTR deltaF508 mutant expressed in FRT cells co-expressing halide-sensitive YFP-H148Q/I152L by fluorescence quenching assay | Homo sapiens | 104 | ALA2062363 | cell-based format | Scientific Literature | |
5. | ALA2067437 | Binding | Inhibition of L-type voltage-dependent Ca2+ channel at 1 uM | Homo sapiens | 104 | ALA2062363 | assay format | Scientific Literature | |
6. | ALA3077039 | Functional | Antifungal activity against Aspergillus flavus up to 200 ug/ml | Aspergillus flavus | 2 | ALA3044536 | organism-based format | Scientific Literature | |
7. | ALA3076518 | Functional | Antifungal activity against Aspergillus niger up to 200 ug/ml | Aspergillus niger | 2 | ALA3044536 | organism-based format | Scientific Literature | |
8. | ALA3076519 | Functional | Antifungal activity against Candida albicans up to 200 ug/ml | Candida albicans | 1 | ALA3044536 | organism-based format | Scientific Literature | |
9. | ALA3076520 | Functional | Anti-inflammatory activity in Homo sapiens (human) THP1 cells assessed as inhibition of LPS-induced IL6 production at 10 uM incubated for 30 min prior to LPS-challenge measured after 24 hr by ELISA | Homo sapiens | 12 | ALA3044536 | cell-based format | Scientific Literature | |
10. | ALA3076521 | Functional | Anti-inflammatory activity in Homo sapiens (human) THP1 cells assessed as inhibition of LPS-induced TNFalpha production at 10 uM incubated for 30 min prior to LPS-challenge measured after 24 hr by ELISA | Homo sapiens | 12 | ALA3044536 | cell-based format | Scientific Literature | |
11. | ALA3076527 | Functional | Antifungal activity against Fusarium solani | Fusarium solani | 12 | ALA3044536 | organism-based format | Scientific Literature | |
12. | ALA3076532 | Functional | Antibacterial activity against Salmonella enterica subsp. enterica serovar Typhimurium | Salmonella enterica subsp. enterica serovar Typhimurium | 13 | ALA3044536 | organism-based format | Scientific Literature | |
13. | ALA3076533 | Functional | Antibacterial activity against Escherichia coli | Escherichia coli | 13 | ALA3044536 | organism-based format | Scientific Literature | |
14. | ALA3076534 | Functional | Antibacterial activity against Bacillus subtilis up to 200 ug/ml | Bacillus subtilis | 3 | ALA3044536 | organism-based format | Scientific Literature | |
15. | ALA3076537 | Functional | Antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | 12 | ALA3044536 | organism-based format | Scientific Literature | |
16. | ALA3412764 | Binding | Inhibition of Saccharomyces cerevisiae alpha-glucosidase using p-nitrophenyl alpha-D-glucopyranoside as substrate preincubated for 15 mins measured up to 30 mins by spectrophotometry | Saccharomyces cerevisiae | 25 | ALA3407409 | single protein format | Scientific Literature | |
17. | ALA3412765 | Binding | Competitive inhibition of Saccharomyces cerevisiae alpha-glucosidase using p-nitrophenyl alpha-D-glucopyranoside as substrate preincubated for 15 mins by Lineweaver-Burk plot method | Saccharomyces cerevisiae | 1 | ALA3407409 | single protein format | Scientific Literature | |
18. | ALA3412767 | Binding | Inhibition of purified bovine erythrocyte carbonic anhydrase 2 using 4-PNA as substrate preincubated for 15 mins by spectrophotometry | Bos taurus | 4 | ALA3407409 | single protein format | Scientific Literature | |
19. | ALA3412768 | Binding | Inhibition of snake venom phosphodiesterase-1 using bis-(p-nitropheny1) phosphate as substrate preincubated for 30 mins by spectrophotometry | Serpentes | 4 | ALA3407409 | assay format | Scientific Literature | |
20. | ALA3412769 | Binding | Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-D-glucuronide as substrate preincubated for 30 mins by spectrophotometry | Homo sapiens | 4 | ALA3407409 | single protein format | Scientific Literature |