# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1114672 | Functional | Activation of Nrf2 in rat PC12 cells at 10 uM after 24 hrs by antioxidant response element-driven luciferase reporter gene assay relative to yangonin | Rattus norvegicus | 1 | ALA1158532 | cell-based format | Scientific Literature | |
2. | ALA1114673 | Functional | Activation of Nrf2 in rat PC12 cells at 10 uM after 24 hrs by antioxidant response element-driven luciferase reporter gene assay relative to kawain | Rattus norvegicus | 1 | ALA1158532 | cell-based format | Scientific Literature | |
3. | ALA1114674 | Functional | Activation of Nrf2 in rat PC12 cells at 10 uM after 24 hrs by antioxidant response element-driven luciferase reporter gene assay relative to methysticin | Rattus norvegicus | 1 | ALA1158532 | cell-based format | Scientific Literature | |
4. | ALA1114675 | Functional | Induction of HO-1 protein expression in rat PC12 cells at 10 uM after 24 hrs by Western blot analysis relative to yangonin | Rattus norvegicus | 1 | ALA1158532 | cell-based format | Scientific Literature | |
5. | ALA1114676 | Functional | Induction of HO-1 protein expression in rat PC12 cells at 10 uM after 24 hrs by Western blot analysis relative to kawain | Rattus norvegicus | 1 | ALA1158532 | cell-based format | Scientific Literature | |
6. | ALA1114677 | Functional | Induction of HO-1 protein expression in rat PC12 cells at 10 uM after 24 hrs by Western blot analysis relative to methysticin | Rattus norvegicus | 1 | ALA1158532 | cell-based format | Scientific Literature | |
7. | ALA1114680 | ADME | Cytotoxicity against rat PC12 cells at 100 uM after 24 hrs by WST8 assay | Rattus norvegicus | 1 | ALA1158532 | cell-based format | Scientific Literature | |
8. | ALA1114681 | ADME | Cytotoxicity against rat PC12 cells assessed as effect on cellular morphology at 50 to 100 uM after 24 hrs by WST8 assay | Rattus norvegicus | 1 | ALA1158532 | cell-based format | Scientific Literature | |
9. | ALA1114682 | Functional | Activation of Nrf2 in rat PC12 cells after 24 hrs by antioxidant response element-driven luciferase reporter gene assay relative to yangonin | Rattus norvegicus | 1 | ALA1158532 | cell-based format | Scientific Literature | |
10. | ALA1114683 | Functional | Increase in HO-1 protein expression in rat PC12 cells at 10 uM after 3 hrs by Western blot analysis | Rattus norvegicus | 1 | ALA1158532 | cell-based format | Scientific Literature | |
11. | ALA1114684 | Functional | Induction of gamma-GCSc catalytic subunit protein expression in rat PC12 cells at 10 uM after 12 hrs by Western blot analysis | Rattus norvegicus | 1 | ALA1158532 | cell-based format | Scientific Literature | |
12. | ALA1114685 | Functional | Increase in NQO1 protein expression in rat PC12 cells at 10 uM after 3 hrs by Western blot analysis | Rattus norvegicus | 1 | ALA1158532 | cell-based format | Scientific Literature | |
13. | ALA1114686 | Functional | Induction of HO-1 protein expression in rat PC12 cells at 10 uM after 24 hrs by Western blot analysis relative to control | Rattus norvegicus | 1 | ALA1158532 | cell-based format | Scientific Literature | |
14. | ALA1114687 | Functional | Induction of gamma-GCSc catalytic subunit protein expression in rat PC12 cells at 10 uM after 24 hrs by Western blot analysis relative to control | Rattus norvegicus | 1 | ALA1158532 | cell-based format | Scientific Literature | |
15. | ALA1114688 | Functional | Induction of NQO1 protein expression in rat PC12 cells at 10 uM after 24 hrs by Western blot analysis relative to control | Rattus norvegicus | 1 | ALA1158532 | cell-based format | Scientific Literature | |
16. | ALA1114689 | Functional | Activation of Nrf2 in rat PC12 cells assessed as induction of translocation into nucleus at 10 uM after 30 mins by Western blot analysis | Rattus norvegicus | 1 | ALA1158532 | cell-based format | Scientific Literature | |
17. | ALA1114690 | Functional | Activation of Nrf2 in rat PC12 cells assessed as induction of translocation into nucleus at 10 uM after 24 hrs by Western blot analysis | Rattus norvegicus | 1 | ALA1158532 | cell-based format | Scientific Literature | |
18. | ALA1114691 | Binding | Increase in Erk1/2 phosphorylation in rat PC12 cells at 10 uM after 5 mins by Western blot analysis | Rattus norvegicus | 1 | ALA1158532 | cell-based format | Scientific Literature | |
19. | ALA1114692 | Binding | Increase in Erk1/2 phosphorylation in rat PC12 cells at 10 uM after 6 hrs by Western blot analysis | Rattus norvegicus | 1 | ALA1158532 | cell-based format | Scientific Literature | |
20. | ALA1114693 | Binding | Increase in p38 phosphorylation in rat PC12 cells at 10 uM after 5 mins by Western blot analysis | Rattus norvegicus | 1 | ALA1158532 | cell-based format | Scientific Literature |